19 products were found matching "AG-40B-0129-C010"!

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Flagellin (NLRC4 Mutant) (rec.)
Flagellin (NLRC4 Mutant) (rec.)

Item number: AG-40B-0126-C010

The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) contains a small deletion at the C-terminus of the protein required for NLRC4 activation and is fused at the N-terminus to a His-tag. Lyophilized. Contains PBS. Flagellin is the subunit protein which polymerizes to...
Keywords: flaF, fliC, STM1959, Flagellin, Phase 1-I flagellin (NLRC4 Mutant)
Application: Human TLR5 activator
Expressed in: E.coli
Origin: human, mouse
215.00€ * From 193.50€ *
Review
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Flagellin (rec.)
Flagellin (rec.)

Item number: AG-40B-0125-C010

The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) is fused at the N-terminus to a His-tag. Lyophilized. Contains PBS. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the...
Keywords: flaF, fliC, STM1959, Flagellin, Phase 1-I flagellin
Application: TLR5 activator, NLRC4 activator
Expressed in: E.coli
Origin: human, mouse
198.00€ * From 178.20€ *
Review
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IL-2 Superkine (Fc) (H9T) [IL-2 (human):Fc (human) (rec.) (H9T)]
IL-2 Superkine (Fc) (H9T) [IL-2 (human):Fc (human) (rec.)...

Item number: AG-40B-0219-C010

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of...
Keywords: IL2, IL-2, TCGF, Aldesleukin, Interleukin-2, T-cell growth factor
Application: Triggers greater antitumor responses by maintaining stem-cell memory phenotype of CD8+ T cells
Expressed in: Human cells
Origin: human, mouse
MW: 42 kD
341.00€ * From 306.90€ *
Review
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FLT3 Ligand (human):Fc (human) (rec.)
FLT3 Ligand (human):Fc (human) (rec.)

Item number: AG-40B-0119-C010

The receptor-binding domain of human FLT3L is fused at the N-terminus to the Fc portion of human IgG1. Liquid. In PBS (sterile). FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors....
Keywords: Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand
Application: Bioassay
Expressed in: Hamster cells
Origin: human, mouse
248.00€ * From 223.20€ *
Review
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BAFF (human):Fc (human) (rec.)
BAFF (human):Fc (human) (rec.)

Item number: AG-40B-0120-C010

The receptor-binding domain of human BAFF (aa 136-285) is fused at the N-terminus to the Fc portion of human IgG1. Liquid. In PBS (sterile). BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some...
Keywords: BLyS, BAFF, CD257, TALL-1, TNFSF13B, B lymphocyte stimulator, B-cell-activating factor, Dendritic cell-derived TNF-like...
Application: Bioassay
Expressed in: Hamster cells
Origin: human, mouse
253.00€ * From 227.70€ *
Review
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Flagellin (TLR5 Mutant) (rec.)
Flagellin (TLR5 Mutant) (rec.)

Item number: AG-40B-0127-C010

The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) contains a substitution of amino acids 90-97 required for TLR5 signaling by a motif from a non-signaling flagellin and is fused at the N-terminus to a His-tag. Lyophilized. Contains PBS. Flagellin is the subunit...
Keywords: flaF, fliC, STM1959, Flagellin, Phase 1-I flagellin (TLR5 Mutant)
Application: Negative control
Expressed in: E.coli
Origin: human, mouse
215.00€ * From 193.50€ *
Review
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IL-38 (aa 20-152) (human) (rec.) (His)
IL-38 (aa 20-152) (human) (rec.) (His)

Item number: AG-40B-0169-C010

Protein function: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic...
Keywords: FIL1T, IL-38, IL1F10, FKSG75, IL-1F10, IL-1HY2, FIL1 theta, IL-1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1...
Application: Cell culture
Expressed in: E.coli
Origin: human
MW: 16 kD
308.00€ * 277.20€ *
Review
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FNDC4 (rec.) (untagged)
FNDC4 (rec.) (untagged)

Item number: AG-40B-0124-C010

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the...
Keywords: FNDC4, FRCP1, Fibronectin type III domain-containing protein 4, Fibronectin type III repeat-containing protein 1
Application: Bioassay
Expressed in: E.coli
Origin: dog, human, monkey, mouse, rat
MW: 16 kD
215.00€ * From 193.50€ *
Review
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POP1 (human) (rec.)
POP1 (human) (rec.)

Item number: AG-40B-0123-C010

Human POP1 (aa 2-89) is fused at the N-terminus to a GST tag. Lyophilized. Contains PBS. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
Keywords: ASC2, PYDC1, PAAD-only protein 1, Pyrin-only protein 1, Pyrin domain-containing protein 1
Application: Bioassay
Expressed in: E.coli
Origin: human
MW: 38 kD
171.00€ * From 153.90€ *
Review
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OX40L (mouse) (multimeric) (rec.)
OX40L (mouse) (multimeric) (rec.)

Item number: AG-40B-0029-C010

The extracellular domain of mouse OX40L (amino acids 52-199) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Activates T cell proliferation. Lyophilized. Contains PBS. OX40L [CD252, CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as...
Keywords: MegaOX40L(TM), Soluble (mouse, rec.), ACRP30headless:OX40L, ACRP30headless:CD252, ACRP30headless:CD134L
Application: Bioassays
Expressed in: Human cells
Origin: human, mouse
MW: 40 kD
220.00€ * 198.00€ *
Review
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Profilin (Toxoplasma gondii)
Profilin (Toxoplasma gondii)

Item number: AG-40B-0121-C010

Recombinant profilin (Toxoplasma gondii) (aa 1-163). Lyophilized. Contains PBS. TLR11, an innate sensor for profilin (Toxoplasma gondii), is an intracellular receptor that resides in the endoplasmic reticulum. The 12 membrane-spanning endoplasmic reticulum-resident protein UNC93B1 interacts directly with TLR11 and...
Keywords: PRF, Profilin, Inflammatory profilin, Profilin family protein
Application: TLR11 / TLR12 ligand
Expressed in: E.coli
Origin: mouse
MW: 20 kD
248.00€ * From 223.20€ *
Review
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Granulin C (human, rec.) (His)
Granulin C (human, rec.) (His)

Item number: AG-40A-0129-C010

Human granulin C (amino acids 364-430) is fused at the N-terminus to a His-tag. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Granulins have possible cytokine-like activity. They are important in normal development, inflammation, wound repair, and tumorigenesis.
Keywords: Granulin-5, GRN C
Application: Bioassays
Expressed in: E.coli
Origin: human
MW: 10 kD
193.00€ * 173.70€ *
Review
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