Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant , Plasma , Serum. Sensitivity: 5pg/ml. Range: 0.016 to 1ng/ml. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. IL-33 affects the various cell types that express membrane ST2, which is selectively expressed by Th2 but not Th1 cells. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy and anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis. In healthy human serum almost no IL-33 could be detected, whereas serum IL-33 levels were significantly increased in chronic active inflammation, like rheumatoid arthritis.
Datenblatt ansehen
Manual
Kat #: AG-45A-0033EK-KI01
Menge: 96 wellsBuy Bulk
Preis: 539 €
404 €
UniProt ID: O95760 (Protein knowledgebase)
Schlagworte:
NF-HEV, Interleukin-33, IL-1F11
Figure legend: Datenblatt ansehen
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-Human IL-33, Kat #: 209-401-B50S
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Plasmids/Vectors
Chemicals & More
ELISA and Assay Kits
Cytokines
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Products for: IL33 - interleukin 33
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