Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to...

Human ANGPTL7 (amino acids 1-346) is fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 cells. Liquid. 0.2µm-filtered solution in PBS. ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...

Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and...

Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor...