IL-10 (human):Fc (human) (rec.) (non-lytic)

IL-10 (human):Fc (human) (rec.) (non-lytic)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-22010-C010 10 µg - -

3 - 9 business days*

264.00€
CHI-HF-22010-C050 50 µg - -

3 - 9 business days*

446.00€
 
The extracellular domain of human IL-10 (aa 19-178) is fused at the C-terminus to the Fc portion... more
Product information "IL-10 (human):Fc (human) (rec.) (non-lytic)"
The extracellular domain of human IL-10 (aa 19-178) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells, and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T-cell mediated autoimmune diseases.
Keywords: IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-22010

Properties

Application: Bioassays
Conjugate: No
Host: Hamster cells
Species reactivity: human
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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