IBMX

IBMX
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13347-100 100 mg -

6 - 10 business days*

50.00€
Cay13347-250 250 mg -

6 - 10 business days*

90.00€
Cay13347-500 500 mg -

6 - 10 business days*

149.00€
Cay13347-1 1 g -

6 - 10 business days*

214.00€
 
IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases... more
Product information "IBMX"
IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases. Methylxanthines, including IBMX, caffeine, and theophylline, bind adenosine receptors, typically antagonizing the suppressive effects of natural agonists.Formal Name: 3,9-dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione. CAS Number: 28822-58-4. Synonyms: Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine, NSC 165960, SC-2964. Molecular Formula: C10H14N4O2. Formula Weight: 222.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, Ethanol: 5 mg/ml. lambdamax: 272 nm. SMILES: CC(C)CN(C1=C2NC=N1)C(N(C)C2=O)=O. InChi Code: InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12). InChi Key: APIXJSLKIYYUKG-UHFFFAOYSA-N.
Keywords: 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, NSC 165960, SC-2964, 3,9-dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Supplier: Cayman Chemical
Supplier-Nr: 13347

Properties

Application: PDE inhibitor
MW: 222.3 D
Formula: C10H14N4O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 28822-58-4| Matching products
KEGG ID : K13298 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P301+310, P330, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "IBMX"
Write a review
or to review a product.
-10 %
IBMX IBMX
121.00€ * From 108.90€ *
Viewed