- Search results for Cay10202-25
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10 products were found matching "Cay10202-25"!
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Item number: Cay12022-5
(-)-WIN 55,212-3 is an aminoalkylindole derivative which acts as a competitive neutral antagonist of the human cannabinoid CB2 receptor, blocking both the stimulating action of CP 55,940 (pA2 = 6.1) and the inverse agonism of SR 144528 (Cay-9000491) (pEC50 = 5.3). (-)-WIN 55,212-3 neither antagonizes nor mimics the...
Keywords: | [(3S)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
Application: | Forensic studies, difuran analog |
CAS | 131543-25-4 |
MW: | 522.6 D |
From 56.00€
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Item number: Cay10022-5
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
Application: | Antitumor agent, Apoptosis inducer |
CAS | 36098-33-6 |
MW: | 362.2 D |
From 19.00€
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Item number: Cay21002-250
(S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist. It inhibits aggregation of rat platelets induced by ADP, collagen, and thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a...
Keywords: | SR 25990C, S-alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate |
Application: | P2Y12 receptor antagonist |
CAS | 120202-66-6 |
MW: | 419.9 D |
From 43.00€
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Item number: Cay10009222-25
Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Keywords: | SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol |
Application: | SPHK1 inhibitor |
CAS | 312636-16-1 |
MW: | 302.8 D |
From 54.00€
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Item number: Cay10009212-25
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Keywords: | N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide |
Application: | PI4K-beta inhibitor |
CAS | 593960-11-3 |
MW: | 389.9 D |
From 43.00€
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Item number: Cay10225-1
To be used in conjunction with Cayman's GPR55 Polyclonal Antibody (Cay-10224) to block protein-antibody complex formation during immunochemical analysis of GPR55 for Western blot (WB).Synonyms: G Protein-Coupled Receptor 55, LIP1, Lysophosphatidylinositol Receptor 1. Formulation: (Request formulation change), 200 µg...
Keywords: | G Protein-Coupled Receptor 55, LIP1, Lysophosphatidylinositol Receptor 1 |
Application: | ICC, IF, IHC, WB |
177.00€
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Item number: Cay10206-25
Secretory phospholipase A2 (sPLA2) (Type IIA) is a calcium-dependent PLA2 superfamily member that is encoded by PLA2G2A in humans. It is composed of a highly-conserved calcium-binding loop, a catalytic domain, sPLA2 Type I- and II-specific disulfides that provide stability, and a C-terminal extension but lacks the...
Keywords: | PLA2B, PLA2G2A, NPS-PLA2, NPS-PLA2, GIIC sPLA2, GIIC sPLA2, Group IIA phospholipase A2, Group IIA phospholipase A2,... |
Application: | Enzyme assays |
Expressed in: | E.coli |
Origin: | human |
566.00€
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Item number: Cay30202-25
SKF 86002 is an anti-inflammatory agent. It inhibits rat seminal vesicle prostaglandin H2 (PGH2) synthase (IC50 = 120 µM), as well as prostanoid production by rat basophilic leukemia (RBL-1) cells and human monocytes (IC50s = 70 and 1 µM, respectively). SKF 86002 inhibits leukotriene B4 (LTB4) and LTC4 production...
Keywords: | 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-imidazo[2,1-b]thiazole |
Application: | Antiinflammatory agent |
CAS | 72873-74-6 |
MW: | 297.4 D |
From 48.00€
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Item number: Cay20225-1
7-Aminoclonazepam (CRM) (Cay-20225) is a certified reference material categorized as a benzodiazepine. It is the primary metabolite of clonazepam (Cay-14263, Cay-ISO60181). This product is intended for research and forensic applications.Formal Name: 7-amino-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one....
Keywords: | Aminoclonazepam, Chloraminazepam, 7-amino-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
Application: | Certified reference material, benzodiazepine, primary clonazepam metabolite |
CAS | 4959-17-5 |
MW: | 285.7 D |
98.00€
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Item number: Cay20210-25
Leukotriene C4 (LTC4) is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A)...
Keywords: | LTC4, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 72025-60-6 |
MW: | 625.8 D |
From 193.00€
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