10 products were found matching "Cay10202-100"!

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Prostaglandin D2 MaxSpec(R) Standard
Prostaglandin D2 MaxSpec(R) Standard

Item number: Cay10007202-100

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Keywords: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
119.00€ *
Review
(±)11(12)-EET MaxSpec(R) Standard
(±)11(12)-EET MaxSpec(R) Standard

Item number: Cay10007262-100

(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET (Cay-50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells. (±)11(12)-EET MaxSpec(R) standard is a quantitative grade standard of (±)11(12)-EET...
Keywords: (±)11,12-EpETrE, (±)11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid
Application: Bioactive lipid assays
MW: 320.5 D
267.00€ *
Review
Fingolimod (hydrochloride)
Fingolimod (hydrochloride)

Item number: Cay10006292-100

Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
Keywords: FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride
Application: Immune Modulator
CAS 162359-56-0
MW: 343.9 D
From 84.00€ *
Review
Zafirlukast
Zafirlukast

Item number: Cay10008282-100

Zafirlukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay). It is selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM). It inhibits mucus secretion induced by leukotriene D4 (LTD4, Cay-20310) in isolated guinea pig trachea (IC50 = 0.6 µM)....
Keywords: [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-carbamic acid,...
Application: CysLT1 receptor antagonist
CAS 107753-78-6
MW: 575.7 D
From 26.00€ *
Review
Cortisol AChE Tracer
Cortisol AChE Tracer

Item number: Cay10005272-100

Formulation: A lyophilized powder. Origin: Animal/Eel.
Application: Tracer
From 236.00€ *
Review
Anti-Phosphotyrosine (Ascites)   (Clone 13F9)
Anti-Phosphotyrosine (Ascites) (Clone 13F9)

Item number: Cay10222-100

Protein phosphorylation is an important post-translational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently...
Application: ELISA, WB
Host: Mouse
530.00€ *
Review
Leukotriene C4
Leukotriene C4

Item number: Cay20210-100

Leukotriene C4 (LTC4) is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A)...
Keywords: LTC4, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 72025-60-6
MW: 625.8 D
From 193.00€ *
Review
(S)-(+)-Clopidogrel (sulfate)
(S)-(+)-Clopidogrel (sulfate)

Item number: Cay21002-100

(S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist. It inhibits aggregation of rat platelets induced by ADP, collagen, and thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a...
Keywords: SR 25990C, S-alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate
Application: P2Y12 receptor antagonist
CAS 120202-66-6
MW: 419.9 D
From 43.00€ *
Review
Daidzin
Daidzin

Item number: Cay13202-100

Daidzin is an isoflavone that occurs naturally in some plants, including soy and kudzu root. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic...
Keywords: NPI 031D, Daidzoside, 7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Application: ALDH2 inhibitor
CAS 552-66-9
MW: 416.4 D
From 52.00€ *
Review
JWH 387
JWH 387

Item number: Cay12020-10

JWH 387 is an analgesic cannabimimetic from the naphthoylindole family that acts as a potent cannabinoid (CB) agonist at both the central CB1 and peripheral CB2 receptors with Ki values of 1.2 and 1.1 nM, respectively. This product is intended for research and forensic purposes.Formal Name:...
Keywords: (4-bromo-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone
Application: Analytical reference standard, Analgesic cannabimimetic, Non-selective potent cannabinoid agonist
CAS 1366067-59-5
MW: 420.3 D
From 291.00€ *
Review