- Search results for Cay10202
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12 products were found matching "Cay10202"!
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Item number: Cay10206-25
Secretory phospholipase A2 (sPLA2) (Type IIA) is a calcium-dependent PLA2 superfamily member that is encoded by PLA2G2A in humans. It is composed of a highly-conserved calcium-binding loop, a catalytic domain, sPLA2 Type I- and II-specific disulfides that provide stability, and a C-terminal extension but lacks the...
Keywords: | PLA2B, PLA2G2A, NPS-PLA2, NPS-PLA2, GIIC sPLA2, GIIC sPLA2, Group IIA phospholipase A2, Group IIA phospholipase A2,... |
Application: | Enzyme assays |
Expressed in: | E.coli |
Origin: | human |
566.00€
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Item number: Cay10272-500
Activation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells with an...
Keywords: | 13-O-Acetylphorbol, NSC 623310, SA 101A,... |
Application: | HIV-1 reactivation |
CAS | 60857-08-1 |
MW: | 390.5 D |
From 92.00€
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Item number: Cay10012201-1
The primary use of this antibody conjugate is for the detection of SPHK1 in intact cells by direct immunolabeling methods such as flow cytometry or immunofluorescence microscopy. SPHK1 is one of the enzymes involved in sphingolipid metabolism. SPHK1 catalyzes the phosphorylation of sphingosine to...
Keywords: | Anti-SK 1, Anti-SK 1, Anti-SPK 1, Anti-SPK 1, Anti-Sphingosine kinase 1, Anti-Sphingosine kinase 1, Anti-Acetyltransferase... |
Application: | FC, WB |
Host: | Rabbit |
Species reactivity: | human |
472.00€
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Item number: Cay10006292-50
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
Keywords: | FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride |
Application: | Immune Modulator |
CAS | 162359-56-0 |
MW: | 343.9 D |
From 84.00€
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Item number: Cay10009222-5
Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Keywords: | SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol |
Application: | SPHK1 inhibitor |
CAS | 312636-16-1 |
MW: | 302.8 D |
From 54.00€
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Item number: Cay10008282-10
Zafirlukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay). It is selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM). It inhibits mucus secretion induced by leukotriene D4 (LTD4, Cay-20310) in isolated guinea pig trachea (IC50 = 0.6 µM)....
Keywords: | [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-carbamic acid,... |
Application: | CysLT1 receptor antagonist |
CAS | 107753-78-6 |
MW: | 575.7 D |
From 26.00€
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Item number: Cay10007262-100
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET (Cay-50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells. (±)11(12)-EET MaxSpec(R) standard is a quantitative grade standard of (±)11(12)-EET...
Keywords: | (±)11,12-EpETrE, (±)11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid |
Application: | Bioactive lipid assays |
MW: | 320.5 D |
267.00€
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Item number: Cay10009292-96
LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. Plasma levels of LTB4 increase from 100 ng/ml following leukocyte stimulation. LTB4 is metabolized in leukocytes and...
Keywords: | LTB4 Express EIA Kit |
Application: | ELISA |
From 459.00€
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Item number: Cay10004272-1
Peroxisome proliferator-activated receptor delta (PPARdelta) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. GW 501516 is the first highly selective synthetic PPARdelta agonist available. GW 501516 binds to human PPARdelta...
Keywords: | GW 1516, 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
Application: | PPAR delta agonist |
CAS | 317318-70-0 |
MW: | 453.5 D |
From 60.00€
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Item number: Cay10009212-10
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Keywords: | N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide |
Application: | PI4K-beta inhibitor |
CAS | 593960-11-3 |
MW: | 389.9 D |
From 43.00€
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Item number: Cay10009232-1
Histone deacetylases (HDACs) catalyze the deacetylation of core histones, resulting in tightening of nucleosomal integrity, restriction of the access of transcription factors, and suppression of transcription. HDACs also play an important role in mediating nuclear receptor functions by forming co-repressor complexes...
Keywords: | Histone Deacetylase 3/Nuclear Receptor Corepressor 2 |
Application: | Enzyme activity |
MW: | 49,7 kD |
678.00€
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Item number: Cay10006212-5
alpha-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7 is a more lipophilic analog of alpha-lipoic acid with enhanced potency and 1.5-fold...
Keywords: | 3-(5-[1,2]dithiolan-3yl-pentanoylamino)-propyl]-amide |
Application: | Alpha-lipoic acid analog |
CAS | 691410-93-2 |
MW: | 450.7 D |
From 43.00€
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