4 products were found matching "SKT-109"!

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(S)-KT109
(S)-KT109

Item number: Cay25683-1

(S)-KT109 is the (S) isomer of the diacylglycerol lipase beta (DAGLbeta) inhibitor KT109 (Cay-18933). (S)-KT109 is a less potent inhibitor of DAGLbeta (IC50 = 39.81 nM), DAGLalpha-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and alpha/beta-hydrolase domain-containing protein 6...
Keywords: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone
Application: Diacylglycerol lipase inhibitor
CAS 2055172-61-5
MW: 422.5 D
From 125.00€ *
Review
(R)-KT109
(R)-KT109

Item number: Cay25682-1

(R)-KT109 is the (R) isomer of the diacylglycerol lipase beta (DAGLbeta) inhibitor KT109 (Cay-18933). (R)-KT109 is an inhibitor of DAGLbeta (IC50 = 0.79 nM) and of DAGLalpha-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (Cay-10008650, IC50 = 25.12 nM). It also inhibits alpha/beta-hydrolase...
Keywords: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2R)-2-(phenylmethyl)-1-piperidinyl]-methanone
Application: Diacylglycerol lipase inhibitor
CAS 2055172-60-4
MW: 422.5 D
From 125.00€ *
Review
KT109
KT109

Item number: Cay18933-1

In humans, two forms of diacylglycerol lipase, DAGLalpha and DAGLbeta, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG, Cay-62160) by attacking DAG at the sn-1 position. KT109 is a selective inhibitor of DAGLbeta with an IC50 value of 42 nM. It demonstrates ~60-fold selectivity for DAGLbeta over...
Keywords: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylmethyl)-1-piperidinyl]-methanone
Application: DAGLB inhibitor
CAS 1402612-55-8
MW: 422.5 D
From 60.00€ *
Review
KT109 N2 Regioisomer
KT109 N2 Regioisomer

Item number: Cay26127-1

KT109 N2 regioisomer is an N2-carbamoylated regioisomer of the diacylglycerol lipase beta (DAGLbeta) inhibitor KT109 (Cay-18933). It is intended for use as an internal standard for the quantification of KT109.Formal Name: (4-[1,1'-biphenyl]-4-yl-2H-1,2,3-triazol-2-yl)[2-(phenylmethyl)-1-piperidinyl]-methanone. CAS...
Keywords: (4-([1,1'-biphenyl]-4-yl)-2H-1,2,3-triazol-2-yl)(2-benzylpiperidin-1-yl)methanone
Application: Antibiotic, bacterial DHFR inhibitor, GC-MS, LC-MS, internal standard
CAS 2749638-90-0
MW: 422.5 D
From 92.00€ *
Review