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Histone H4 (human, recombinant)
Histone H4 (human, recombinant)

Item number: Cay10264-100

A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H4 undergoes many...
Keywords: H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4-16, HIST4H4, Histone H4, Histone H4
Application: TR-FRET
Expressed in: E.coli
Origin: human
MW: 11,5 kD
130.00€ *
Review
13,14-dihydro-15-keto Prostaglandin A2
13,14-dihydro-15-keto Prostaglandin A2

Item number: Cay10260-5

PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin. Further decomposition of...
Keywords: 13,14-dihydro-15-keto PGA2, 9,15-dioxo-prosta-5Z,10-dien-1-oic acid
Application: Bioactive lipid assays
CAS 74872-89-2
MW: 334.5 D
From 119.00€ *
Review
Brexpiprazole-d8
Brexpiprazole-d8

Item number: Cay26450-500

Brexpiprazole-d8 is intended for use as an internal standard for the quantification of brexpiprazole (Cay-22906) by GC- or LC-MS. Brexpiprazole is a serotonin (5-HT) and dopamine receptor modulator that has high affinity (Ki = 1A and 5-HT2A serotonin, dopamine D2L, and alpha1B-, and alpha2C-adrenergic receptors in...
Keywords: 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)butoxy]-2(1H)-quinolinone
Application: GC-MS, LC-MS, Quantification, Internal standard, Serotonin-dopamine activity modulator (SDAM)
CAS 1427049-21-5
MW: 441.6 D
From 352.00€ *
Review
U-46619
U-46619

Item number: Cay16450-1

U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist. It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0,...
Keywords: 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha, 9,11-dideoxy-9alpha,11alpha-methanoepoxy Prostaglandin F2alpha,...
Application: TP receptor agonist
CAS 56985-40-1
MW: 350.5 D
From 130.00€ *
Review