- Search results for Cay10263-50
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16 products were found matching "Cay10263-50"!
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Item number: Cay10005263-50
Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines. TOFA is an inhibitor of fatty acid synthesis blocking the synthesis of malonyl-CoA by acetyl-CoA carboxylase (ACC). Both cerulenin (at about 10 µg/ml) and TOFA (at about 1...
Keywords: | 5-(Tetradecyloxy)-2-furoic Acid, RMI 14514, 5-(tetradecyloxy)-2-furancarboxylic acid |
Application: | Bioactive lipid assays |
CAS | 54857-86-2 |
MW: | 324.5 D |
From 50.00€
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Item number: Cay10263-1
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei. It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various...
Keywords: | H3FA, H3FL, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone... |
Application: | WB |
Expressed in: | E.coli |
MW: | 15,5 kD |
732.00€
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Item number: Cay10260-5
PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin. Further decomposition of...
Keywords: | 13,14-dihydro-15-keto PGA2, 9,15-dioxo-prosta-5Z,10-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 74872-89-2 |
MW: | 334.5 D |
From 119.00€
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Item number: Cay10253-100
Doxifluridine is an intermediary prodrug of fluorouracil (Cay-14416), the pyrimidine analog that inhibits thymidylate synthase selectively in tumor cells, interfering with DNA synthesis. Doxifluridine is one of two intermediary metabolites formed during metabolic conversion of the chemotherapeutic prodrug,...
Keywords: | 5-DFUR, Ro 21-9738, 5'-deoxy-5-fluoro-uridine |
Application: | Intermediary metabolite of Capecitabine |
CAS | 3094-09-5 |
MW: | 246.2 D |
From 84.00€
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Item number: Cay16350-1
8-iso PGF2alpha is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2alpha...
Keywords: | 15-F2t-Isoprostane, 8-epi PGF2alpha, 8-iso-15(S)-Prostaglandin F2alpha, 8-Isoprostane, iPF2alpha-III,... |
Application: | TP receptor agonist |
CAS | 27415-26-5 |
MW: | 354.5 D |
From 220.00€
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Item number: Cay16063-250
Corticosterone is a steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors. It is produced in response to ACTH (corticotropic hormone) and is the precursor to aldosterone synthesis. Since the production of glucocorticoids is increased by stress,...
Keywords: | 11beta,21-DHP, 11beta,21-dihydroxy Progesterone, 17-deoxy Cortisol, NSC 9705, 11beta,21-dihydroxy-pregn-4-ene-3,20-dione |
Application: | Steroid hormone, Aldosterone precursor, Stress biomarker, Mineralocorticoid receptor agonist |
CAS | 50-22-6 |
MW: | 346.5 D |
From 43.00€
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Item number: Cay10250-1
Programmed cell death protein 4 (PDCD4) levels are elevated during apoptosis and absent in many cancer samples. Loss of PDCD4 expression is an important event in cancer cell progression whereas the restoration of PDCD4 protein can lower metalloproteinase activity and possible metastasis. The known isoforms of PDCD4...
Keywords: | Anti-H731, Anti-PDCD4, Anti-Protein 197/15a, Anti-Protein 197/15a, Anti-Nuclear antigen H731-like, Anti-Nuclear antigen... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay16253-50
GNF-2 is an allosteric inhibitor of Bcr-Abl (IC50 = 267 nM). It is selective for Bcr-Abl over c-Abl and a panel of 63 additional kinases at 10 µM. It inhibits proliferation of Ba/F3 cells (IC50 = 138 nM). GNF-2 (10 µM) reduces viral titers in Vero cells infected with infectious bronchitis virus (IBV), a coronavirus,...
Keywords: | Bcr-Abl Inhibitor, 3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-benzamide |
Application: | Bcr-abl inhibitor |
CAS | 778270-11-4 |
MW: | 374.3 D |
From 125.00€
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Item number: Cay13263-500
AA-861 is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 0.8 µM). It is greater than 100-fold selective for 5-LO over 12-LO and cyclooxygenase (COX). AA-861 inhibits the production of 5-HETE and leukotriene B4 (LTB4, Cay-20110, Cay-10007240) induced by A23187 (Cay-22030) with IC50 values of 0.03 and 0.08 µM,...
Keywords: | A-61589, Docebenone, 2-(12-hydroxy-5,10-dodecadiyn-1-yl)-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione |
Application: | 5-LO inhibitor |
CAS | 80809-81-0 |
MW: | 326.4 D |
From 222.00€
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Item number: Cay16250-500
5-trans PGF2beta is the 9beta-hydroxy isomer of 5-trans PGF2alpha. There are no published reports on the biological activity of this compound.Formal Name: 9beta,11alpha,15S-trihydroxy-prosta-5E,13E-dien-1-oic acid. CAS Number: 36150-02-4. Synonyms: 5-trans-9beta-Prostaglandin F2alpha, 5,6-trans PGF2beta. Molecular...
Keywords: | 5,6-trans PGF2beta, 5-trans-9beta-Prostaglandin F2alpha, 9beta,11alpha,15S-trihydroxy-prosta-5E,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 36150-02-4 |
MW: | 354.5 D |
From 61.00€
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Item number: Cay13026-50
N-3-oxo-decanoyl-L-Homoserine lactone is a quorum-sensing signaling molecule that is produced by bacteria in response to increasing cell density. It increases expression of the bacterial conjugation gene tra in A. tumefaciens in a reporter cell assay. N-3-oxo-decanoyl-L-Homoserine lactone (100 nM) induces...
Keywords: | 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-decanamide |
Application: | Quorum-sensing signaling molecule |
CAS | 147795-40-2 |
MW: | 269.3 D |
From 52.00€
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Item number: Cay26350-5
Denatonium (benzoate salt) (Cay-26350) is an analytical reference standard categorized as a bittering agent. Formulations containing denatonium have been used as bittering agents to reduce ingestion of toxic substances by children. This product is intended for research and forensic applications.Formal Name:...
Keywords: | Lidocaine benzyl benzoate, NSC 157658, WIN 16,568,... |
Application: | Analytical reference standard, bittering agent |
CAS | 3734-33-6 |
MW: | 446.6 D |
60.00€
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