Hexanoyl-Lys [HEL] ELISA Kit

Hexanoyl-Lys [HEL] ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
JAI-KHL-700E 1 kit

3 - 9 business days*

959.00€
 
Oxidative damage of lipids caused by reactive oxygen species (ROS) play an important role in some... more
Product information "Hexanoyl-Lys [HEL] ELISA Kit"
Oxidative damage of lipids caused by reactive oxygen species (ROS) play an important role in some diseases, lesion of cell functions and aging. Aldehydes such as malondi-aldehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) have been reported as one of the advanced lipid peroxidation products. But recently in the earlier stage of lipid peroxidation, 13-hydroperoxyoctadecanoic acid (13-HPODE) is found to be covalently bound to proteins1). Hexanoyl-Lysine adduct (HEL) is a novel lipid hydroperoxide-modified lysine residues. HEL is formed by oxidative modification by oxidized omega-6 fatty acids such as linoleic acid or arachidonic acid. HEL may be a useful biomarker for initial stage of lipid peroxidation.Monoclonal antibodies and ELISA kit have been developped, and HEL can be detected in oxidatively modified LDL, in human atherosclerotic lesions, human urine and serum. It is also reported that HEL is formed in rat muscle during exercise, and the formation is prohibited by antioxidants such as flavonoids.
Keywords: Biomarker lipid oxidation, Molecular Aging
Supplier: JaICA
Supplier-Nr: KHL-700E

Properties

Application: Lipid oxidation detection, ELISA
Format: Solid Phase

Database Information

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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