Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF)

Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97295.5 5 µg - -

3 - 10 business days*

94.00€
97295.20 20 µg - -

3 - 10 business days*

208.00€
97295.1 1 mg - -

3 - 10 business days*

5,242.00€
 
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional... more
Product information "Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF)"
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. (www.uniprot.org) Human recombinant HDGF protein is a single, non-glycosilated, polypeptide chain produced in E.coli, having a molecular weight of 11.5kDa and containing 100 amino acids. HDGF is a member of the hepatoma-derived growth factor family. HDGF plays a role as a secreted mitogen from the human hepatoma cell line Huh-7. HDGF is a nuclear targeted vascular smooth muscle cell mitogen as well as a heparin-binding protein that is greatly expressed in tumor cells where it stimulates proliferation. HDGF takes part in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. HDGF plays a role in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation. HDGF is linked with tumorigenesis and the growth of cancer. HDGF is a self-regulating factor connected with the prognosis of liver cancer, non-small cell lung cancer and pancreatic cancer. HDGF has proliferative, angiogenic, and neurotrophic activity. HDGF is a distinctive nuclear targeting growth factor that is vastly expressed in HCC cells and is a prognostic factor for HCC.
Keywords: High-mobility group protein 1-like 2, HMG1L2, HMG-1L2, Hepatoma-derived growth factor, HDGF, FLJ96580, DKFZp686J1764
Supplier: Biomol GmbH
Supplier-Nr: 97295

Properties

Application: Bioassay
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 11500 D
Purity: >95%
Format: Purified

Database Information

KEGG ID : K16641 | Matching products
UniProt ID : P51858 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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