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HMGB1 (human) (rec.) (His)
HMGB1 (human) (rec.) (His)

Item number: CHI-HR-200HMGB1-C025

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac,...
Keywords: HMG1, HMG-1, HMGB1, High mobility group protein 1, High mobility group protein B1
Application: Bioassays
Expressed in: E.coli
Origin: human
325.00€ *
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