2 products were found matching "Cay11923"!

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Item number: Cay11923-50

Transient receptor potential cation channel A1 (TRPA1) is an ankyrin-like ion channel which acts as a sensor for chemical irritants, pain, and cold. It is activated by allyl isothiocyanate (AITC), formalin, hydrogen peroxide, tear gas, and other compounds. HC-030031 is a selective TRPA1 blocker, antagonizing...

Keywords:	1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide
Application:	TRPA1 blocker
CAS	349085-38-7
MW:	355.4 D

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Radotinib

Item number: Cay19923-1

Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl, with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form. Radotinib also inhibits platelet-derived growth factor receptors (PDGFRs) alpha...

Keywords:	IY-5511,...
Application:	Bcr-Abl tyrosine kinase & PDGFR inhibitor
CAS	926037-48-1
MW:	530.5 D

From 43.00€ *

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