- Search results for Cay16880
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10 products were found matching "Cay16880"!
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Item number: Cay16880-25
Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and...
Keywords: | 5'-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt |
Application: | Nonhydrolyzable GTP analog |
CAS | 64564-03-0 |
MW: | 545.9 D |
From 64.00€
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Item number: Cay16680-10
Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Cay-16681), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered...
Keywords: | 13,14-dihydro-15-keto-20-ethyl PGF2alpha, 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2alpha,... |
Application: | Bioactive lipid assays |
CAS | 120373-36-6 |
MW: | 382.5 D |
From 82.00€
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Item number: Cay16800-10
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
Keywords: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
Application: | PI3K gamma / delta inhibitor |
CAS | 1201438-56-3 |
MW: | 416.9 D |
From 92.00€
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Item number: Cay16889-50
DL-alpha-Difluoromethylornithine (DFMO) is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. DFMO displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine...
Keywords: | DFMO, Eflornithine, 2-(difluoromethyl)-ornithine, monohydrochloride, monohydrate |
Application: | Irreversible ornithine decarboxylase inhibitor, polyamine biosynthesis inhibitor |
CAS | 96020-91-6 |
MW: | 236.6 D |
From 32.00€
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Item number: Cay16883-10
FUB-NPB-22 is an analog of NPB-22 in which the pentyl side chain is replaced by a 4-fluorobenzyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.Formal Name: 1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxylic acid,...
Keywords: | 5-fluoro NIN, FUB-PB-22 indazole analog, 1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxylic acid, 8-quinolinyl ester |
Application: | Analytical reference standard, Synthetic cannabinoid NPB-22 analog |
CAS | 2244864-90-0 |
MW: | 397.4 D |
From 109.00€
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Item number: Cay16884-50
AM2201 (Cay-10707) is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. EG2201 is an analog of AM2201 that has a benzene ring attached to the aminoalkylindole group, positioned adjacent to the naphthoyl...
Keywords: | [9-(5-fluoropentyl)-9H-carbazol-3-yl]-1-naphthalenyl-methanone |
Application: | Analytical reference material, Synthetic cannabinoid AM2201 analog |
CAS | 2365471-72-1 |
MW: | 409.5 D |
From 109.00€
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Item number: Cay16888-10
Pyr3 is a pyrazole compound that selectively antagonizes the transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 µM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05...
Keywords: | 1-[4-[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid, ethyl ester |
Application: | TRPC3 antagonist |
CAS | 1160514-60-2 |
MW: | 456.6 D |
From 43.00€
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Item number: Cay16882-10
Clozapine-N-oxide is a major metabolite of clozapine (Cay-12059) and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively). It...
Keywords: | CNO, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
Application: | Clozapine metabolite |
CAS | 34233-69-7 |
MW: | 342.8 D |
From 48.00€
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Item number: Cay16885-50
Evodiamine is a natural indole alkaloid found in the fruits of Wu Zhu Yu, a plant used in traditional Chinese medicine. Studies involving evodiamine have demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions. It can act as an aryl hydrocarbon antagonist (Ki = 28 nM), activator...
Keywords: | D-Evodiamine, 8,13,13bS,14-tetrahydro-14-methyl-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one |
Application: | Quinazoline alkaloid, AhR antagonist, K05222 activator |
CAS | 518-17-2 |
MW: | 303.4 D |
From 50.00€
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Item number: Cay16887-10
The glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are responsible for a majority of nutrient-stimulated insulin secretion. After being released into the circulation, GIP and GLP-1 are inactivated by the circulating enzyme dipeptidyl peptidase IV (DPP IV). DPP IV inhibitors...
Keywords: | (2S,3S)-2-amino-3-methyl-1-(3-thiazolidinyl)-1-pentanone, 2E-butenedioate (2:1) |
Application: | DPP IV inhibitor |
CAS | 251572-86-8 |
MW: | 260.4 D |
From 66.00€
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