Growth-regulated protein alpha (GRO alpha, KC), human recombinant (rHuGRO alpha)

Growth-regulated protein alpha (GRO alpha, KC), human recombinant (rHuGRO alpha)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G8975-16.5 5 µg - -

3 - 19 business days*

493.00€
G8975-16.25 25 µg - -

3 - 19 business days*

644.00€
 
Three human MGSA/GRO genes encode 3 highly related chemokines, MGSA/GRO alpha, -beta and -gamma.... more
Product information "Growth-regulated protein alpha (GRO alpha, KC), human recombinant (rHuGRO alpha)"
Three human MGSA/GRO genes encode 3 highly related chemokines, MGSA/GRO alpha, -beta and -gamma. All 3 MGSA/GRO proteins bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. Melanoma growth stimulatory activity/gro alpha (MGSA), a member of the alpha-chemokine family, is produced by a variety of dermal and epidermal cells and can act in a paracrine and autocrine fashion. Description: Recombinant Human GRO-alpha produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7811 Dalton. Recombinant Human GRO-alpha is purified by proprietary chromatographic techniques. Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Ser-Val-Ala-Thr. Biological Activity: Recombinant Melanoma growth stimulatory activity is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract human neutrophils cells using a conc. of 10.0-100.0 ng/ml. Protein Content: Protein quantitation was carried out by two independent methods:, 1. UV spectroscopy at 280 nm ., 2. Analysis by RP-HPLC, using a calibrated solution of MGSA as a Reference Standard. Solubility: It is recommended to reconstitute the lyophilized GRO-alpha in sterile 18MOmega-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Stability: Lyophilized MGSA/GRO-a although stable at room temperature for 3 weeks, should be stored desiccated below -180C. Upon reconstitution MGSA/GRO-alpha should be stored at 40C between 2-7 days and for future use below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Supplier: United States Biological
Supplier-Nr: G8975-16

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
Format: Highly Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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