Growth Differentiation Factor 5, His Tag, human recombinant (rHuGDF5-His)

Growth Differentiation Factor 5, His Tag, human recombinant (rHuGDF5-His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97267.5 5 µg - -

3 - 10 business days*

94.00€
97267.25 25 µg - -

3 - 10 business days*

208.00€
97267.1 1 mg - -

3 - 10 business days*

3,952.00€
 
Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the... more
Product information "Growth Differentiation Factor 5, His Tag, human recombinant (rHuGDF5-His)"
Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Human recombinant GDF5 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (fragment 382-501) and having a total molecular mass of 15.8 kDa. GDF5 is fused to 20 amino acid His Tag at N-terminus. GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia (Hunter-Thompson type), brachydactyly (type C) and chondrodysplasia (Grebe type). These associations confirm that the gene product plays a role in skeletal development.
Keywords: Cartilage-derived morphogenetic protein-1, CDMP-1, LAP4, SYNS2, GDF-5, Radotermin, CDMP1, GDF5, Growth differentiation factor 5, BMP-14
Supplier: Biomol GmbH
Supplier-Nr: 97267

Properties

Application: Bioassay
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 15800 D
Purity: >95%
Format: Purified

Database Information

KEGG ID : K04664 | Matching products
UniProt ID : P43026 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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