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White to off-white solid. Soluble in DMSO, slightly soluble in ethanol. Insoluble in water. Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades, Inhibitor of mammalian DNA topoisomerase II, Anticancer agent, inducing cell cycle arrest and apoptosis, Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis, Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers, Potent alpha-glucosidase inhibitor, Anthelmintic, Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities, Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes, Stimulator of autophagy vacuolization, Antioxidant, TRAIL sensitizer, Acts as an agonist at the GPR30 receptor, DNA methyltransferase inhibitor, Genistein exhibits synergistic antibacterial effects on MRSA.
Keywords:
NSC 36586, Baichanin A, Differenol A, 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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