- Search results for Cay11690
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7 products were found matching "Cay11690"!
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Item number: Cay11690-10
Gemcitabine is an active metabolite of the gemcitabine prodrugs NUC-1031 (Cay-9003247) and gemcitabine elaidate (Cay-28303) and a prodrug form of gemcitabine di- and triphosphates. Gemcitabine is phosphorylated by intracellular kinases to the intermediate metabolite gemcitabine monophosphate (Cay-31726) and the...
Keywords: | DDFC, LY 188011, NSC 613327, 2'-deoxy-2',2'-difluoro-cytidine |
Application: | Antiretroviral activity, Apoptosis inducer |
CAS | 95058-81-4 |
MW: | 263.2 D |
From 68.00€
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Item number: Cay16990-50
Prostaglandin F3alpha (PGF3alpha) is a COX product of EPA. The biosynthesis of PGF3alpha from EPA was demonstrated in vitro in human and rabbit ocular tissues. It has only 25% affinity at the ovine luteal FP receptor compared to PGF2alpha.Formal Name: 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid....
Keywords: | PGF3alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 745-64-2 |
MW: | 352.5 D |
From 98.00€
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Item number: Cay11694-50
DNA topoisomerases relax DNA torsional strain created during replication, transcription, recombination, repair, and chromosome condensation. The relaxation of DNA supercoiling by topoisomerase I at single-strand breaks enables anticancer agents to reversibly trap the complex by intercalating between DNA base pairs...
Keywords: | MAG-CPT, NSC 94600, (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
Application: | Topoisomerase inhibitor |
CAS | 7689-03-4 |
MW: | 348.4 D |
From 35.00€
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Item number: Cay11697-10
The peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARalpha (IC50 = 240 nM). It drives the displacement of coactivators...
Keywords: | N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)e... |
Application: | PPARalpha antagonist |
CAS | 880635-03-0 |
MW: | 619.7 D |
From 60.00€
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Item number: Cay11695-50
Catharanthine is an indole alkaloid that has been found in C. roseus and has diverse biological activities. It is a precursor in the biosynthesis of the antimitotic agents vinblastine (Cay-11762) and vincristine (Cay-11764). Catharanthine (320 µM) inhibits microtubule assembly and the proliferation of HCT116 colon...
Keywords: | (+)-3,4-Didehydrocoronaridine, (2alpha,5beta,6alpha)-3,4-didehydro-ibogamine-18beta-carboxylic acid, methyl ester |
Application: | Vinblastine and vincristine precursor, Cancer studies |
CAS | 4168-17-6 |
MW: | 336.4 D |
From 52.00€
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Item number: Cay11693-10
beta-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities. It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 µM but is less potent than its derivative 3-acetyl-11-keto-beta-boswellic acid (Cay-11672). It inhibits cell proliferation in...
Keywords: | (3alpha,4beta)-3-hydroxy-urs-12-en-23-oic acid |
Application: | ALOX5 inhibitor |
CAS | 631-69-6 |
MW: | 456.7 D |
From 60.00€
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Item number: Cay11692-10
alpha-Boswellic acid is a pentacyclic triterpene and an isomer of beta-boswellic acid (Cay-11693) originally isolated from B. serrata. It increases Survivin and Reelin expression, decreases production of reactive oxygen species (ROS) and levels of hyperphosphorylated Tau, and inhibits apoptosis induced by...
Keywords: | (4beta)-3alpha-hydroxy-olean-12-en-23-oic acid |
Application: | Bioactive pentacyclic triterpene |
CAS | 471-66-9 |
MW: | 456.7 D |
From 66.00€
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