Geldanamycin binds specifically to heat shock protein HSP90, inhibits protein maturation. Melting Point: 261-266.5ºC, Elemental Analysis: Calculated, C: 60.19%, H: 7.32%, N: 4.84, Solubility: Soluble in DMSO at 100mg/ml. Poorly soluble in methanol, ethanol and water, Not recommended for stock solutions. Maximum...

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix, (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma...

Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP...

GTF2B, also known as transcription factor II B, is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. The protein serves as a bridge between IID, the...