- Search results for Cay16329
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9 products were found matching "Cay16329"!
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Item number: Cay16329-5
BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3'-oxime, or BIO (Cay-13123). It potently inhibits GSK3alpha/beta (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 µM, respectively). BIO-Acetoxime has been used to study the role of GSK3 in the...
Keywords: | 6-Bromoindirubin-3'-acetoxime, GSK3 Inhibitor X,... |
Application: | GSK3alpha/beta inhibitor |
CAS | 740841-15-0 |
MW: | 398.2 D |
From 43.00€
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Item number: Cay16369-25
Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA. At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis...
Keywords: | 13R,14S-diHDHA, 13R,14S-dihydroxy Docosahexaenoic Acid, MaR2, 13R,14S-dihydroxy-4Z,7Z,9E,11E,16Z,19Z-docosahexaenoic acid |
Application: | Macrophage mediator |
CAS | 1639809-46-3 |
MW: | 360.5 D |
From 104.00€
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Item number: Cay16309-25
Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis. XL888 is an ATP-competitive inhibitor of Hsp90. Through this action, specific client proteins are degraded, resulting in cell cycle arrest or apoptosis. XL888...
Keywords: | N1-[(3-endo)-8-[5-(cyclopropylcarbonyl)-2-pyridinyl]-8-azabicyclo[3.2.1]oct-3-yl]-2-methyl-5-[[(1R)-1-methylpropyl]amino]-... |
Application: | Hsp90 inhibitor |
CAS | 1149705-71-4 |
MW: | 503.6 D |
From 66.00€
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Item number: Cay16379-25
Chitobiose is a dimer of beta-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by...
Keywords: | Peracetylchitobiose,... |
Application: | Chitobiose oxazoline synthesis |
CAS | 41670-99-9 |
MW: | 676.6 D |
From 48.00€
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Item number: Cay16932-1
Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, and...
Keywords: | di-delta-lactone Limonoic Acid,... |
Application: | Antiproliferative, Proapoptotic |
CAS | 1180-71-8 |
MW: | 470.5 D |
From 77.00€
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Item number: Cay13369-25
Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as...
Keywords: | tetranor-Prostaglandin A Metabolite, 5R-(2-carboxyethyl)-epsilon,4-dioxo-2-cyclopentene-1S-octanoic acid |
Application: | Prostaglandin studies |
CAS | 52510-53-9 |
MW: | 310.3 D |
From 164.00€
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Item number: Cay15369-25
Amprenavir is an inhibitor of HIV protease (Ki = 0.04 nM). It inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 = 150 nM). Formulations containing amprenavir have been used in combination with other antiretroviral agents in the treatment of HIV-1 infection.Formal Name:...
Keywords: | 141W94, APV, Prozei, VX-478,... |
Application: | HIV-1 aspartic protease inhibitor |
CAS | 161814-49-9 |
MW: | 505.6 D |
From 125.00€
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Item number: Cay10006329-10
Synthetic manganese-porphyrin complexes have been documented to act as scavengers for oxidative species such as peroxynitrite, superoxide, and hydrogen peroxide. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity. EUK 134 is a salen-manganese...
Keywords: | chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-kappaN)methylidyne]]bis[6-methoxyphenolato-kappaO]]]-manganese |
Application: | Antioxidant |
CAS | 81065-76-1 |
MW: | 416.7 D |
From 52.00€
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Item number: Cay16239-5
ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor. The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and cholesterol. Furthermore, as a key enzyme for linking glucose and lipid...
Keywords: | 3,5-dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide |
Application: | ATP citrate lyase (ACL) inhibitor |
CAS | 943962-47-8 |
MW: | 424.3 D |
From 125.00€
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