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GSK-J1 (sodium salt)
GSK-J1 (sodium salt)

Item number: Cay12054-5

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC50s = 18 and 56 µM, respectively as measured by mass...
Keywords: N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, monosodium salt
Application: JMJD3 inhibitor
CAS 1797832-71-3
MW: 411.4 D
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