GRO-gamma (CXCL3), human recombinant (rHuGRO-g)

Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 73 amino acids. CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called