Gö 6983

Gö 6983 inhibits several isoforms of protein kinase C (PKC, IC50 = 7, 7, 6, 10, 60, and 20,000 nM for PKCalpha, PKCbeta, PKCgamma, PKCdelta, PKCzeta, and PKCµ, respectively). It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.Formal Name: 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione. CAS Number: 133053-19-7. Molecular Formula: C26H26N4O3. Formula Weight: 442.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7) (1:10): 0.1 mg/ml, DMSO: 10 mg/ml. SMILES: COc1ccc2n(CCCN(C)C)cc(C3=C(C(=O)NC3=O)c3c[nH]c4ccccc34)c2c1. InChi Code: InChI=1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32). InChi Key: LLJJDLHGZUOMQP-UHFFFAOYSA-N.