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Item number: Cay62580-5

Fumonisin B1 (FB1) is a mycotoxin that has been found in F. moniliforme. It inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme). FB1 induces DNA fragmentation and apoptosis in CV-1 cells when used at concentrations of 5 and 25 µM, respectively. It is cytotoxic to primary rat hepatocytes and induces...

Keywords:	FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,...
Application:	Ceramide synthase inhibitor
CAS	116355-83-0
MW:	721.8 D

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