12 products were found matching "F6070-06C.100"!

During apoptosis, beta actin is cleaved by activated caspase 3 between Asp244 and Gly245. This cleavage results in the release of an approximately 130 amino acid (15kD) fragment from the C-terminus of beta actin and a 32kD (244 amino acid) N-terminal fragment of actin, known as Fractin. The C-terminus of the Fractin...

FHL proteins are tissue specific cofactors of CREB and CREM and participate in regulation of various physiological processes. These proteins are characterized by the presence of 4 LIM domains and a LIM-half domain at the N-terminus. ACT, a 33kD protein, is a novel member of this family. It is specifically expressed...

Prealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). It is reported to be either selectively transported across or synthesized within the...

Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes,responsible for microbicidal...

The Src family of protein tyrosine kinases (including Src, Lyn, Fyn, Yes, Lck, Blk, Hck, etc.) is important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation of Tyr416 in the activation...

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:4000, Western Blot: 1-3ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and...

Human CD9 is strongly expressed on platelets, on early B cells and on activated T cells. CD9 is a member of the tetraspan family crossing the membrane four times. Both the N-terminal and C-terminal regions are on the cytoplasmic side of the plasma membrane. Recent studies indicate CD9 may be involved with calcium...

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament...

Syk is a cytoplasmic 72kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation,...

Downstream of kinase 3 (DOK3) is a 53kD (predicted) member of the DOK family of cytoplasmic adaptor proteins and is expressed in B cells and macrophages. It contains one pleckstrin homology region (aa63-179) and an IRS-type phosphotyrosine binding domain (PTB) (aa213-317). Alternate splicing generates additional...

This antibody precipitates a heterodimer of Mr 90kD (two bands of Mr 40kD and 50kD upon reduction) on chicken peripheral blood T cells.1,2 Deglycosylation of the heterodimer yields two polypeptides of Mr 35kD and 32kD from antibody precipitates. Unlike human and mouse, in which gamma/delta cells comprise a minor...

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at...