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Flavopiridol (hydrochloride)
Flavopiridol (hydrochloride)

Item number: Cay10009197-5

Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
Keywords: Alvocidib, HL 275, HMR 1275, L-868,275,...
CAS 131740-09-5
MW: 438.3 D
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