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Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 243 amino acids.
Keywords: | Tumor-derived hypophosphatemia-inducing factor, HYPF, ADHR, HPDR2, PHPTC, FGF23, FGF-23, Fibroblast Growth Factor-23 |
Supplier: | Biomol GmbH |
Supplier-Nr: | 94961 |
Properties
Application: | Cell biology studies |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 28000.00 D |
Format: | Lyophilized |
Database Information
KEGG ID : | K22428 | Matching products |
UniProt ID : | Q9GZV9 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |