10 products were found matching "Cay17295"!

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Ferrostatin-1
Ferrostatin-1

Item number: Cay17729-5

Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Cay-17754, EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 µM. Ferrostatin-1 (0.5 µM) inhibits erastin-induced...
Keywords: Fer-1, 3-amino-4-(cyclohexylamino)-benzoic acid, ethyl ester
Application: Ferroptosis inhibitor
CAS 347174-05-4
MW: 262.4 D
From 68.00€ *
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Fendiline (hydrochloride)
Fendiline (hydrochloride)

Item number: Cay17295-1

Fendiline is an alpha2-adrenergic receptor antagonist (Kd = 2.6 µM) and an L-type calcium channel blocker (IC50 = 17 µM) well-known for its coronary vasodilator effects. Fendiline has recently been reported to inhibit K-Ras plasma membrane localization (IC50 = 9.64 µM), which prevents K-Ras signal transduction and...
Keywords: gamma-phenyl-N-(1-phenylethyl)-benzenepropanamine, monohydrochloride
Application: alpha2-adrenergic receptor antagonist, L-type calcium channel blocker
CAS 13636-18-5
MW: 351.9 D
From 46.00€ *
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5-methoxy EiPT
5-methoxy EiPT

Item number: Cay17299-5

5-methoxy EiPT is a tryptamine-based designer drug with structural similarity to 5-methoxy DiPT (Cay-11865) and 5-methoxy MiPT (Cay-11482). While analytical methods have been developed for its identification, the biological activity of 5-methoxy EiPT has not been reported. This product is intended for forensic and...
Keywords: 5-methoxy-N-ethyl-N-Isopropyltryptamine, N-ethyl-5-methoxy-N-(1-methylethyl)-1H-indole-3-ethanamine
Application: Analytical reference standard, Tryptamine-based designer drug
CAS 850032-66-5
MW: 260.4 D
From 280.00€ *
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1-Naphthyl 3,5-dinitrobenzoate
1-Naphthyl 3,5-dinitrobenzoate

Item number: Cay11729-5

1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively. The scaffold of this compound is being explored for anti-inflammatory drug design.Formal Name: 1-(3,5-dinitrobenzoate) 1-naphthalenol. CAS...
Keywords: 1-(3,5-Dinitrobenzoyloxy)naphthalene, 1-Naphthalonol 3,5-dinitrobenzoate, 1-(3,5-dinitrobenzoate) 1-naphthalenol
Application: Dual 5-lipoxygenase & microsomal prostaglandin E synthase-1 inhibitor
CAS 93261-39-3
MW: 338.3 D
From 43.00€ *
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MiPT
MiPT

Item number: Cay17296-5

MiPT is the methyl isopropyl tryptamine base for a series of psychedelic designer drugs, including 5-methoxy MiPT (Cay-11483) and 4-hydroxy MiPT (Cay-11552). Screening for this and related compounds by LC-MS/MS has been reported. The physiological and toxicological properties of this compound are not known. This...
Keywords: N-Methyl-N-Isopropyltryptamine, N-methyl-N-(1-methylethyl)-1H-indole-3-ethanamine
Application: Analytical reference standard, Psychedelic designer drug base
CAS 96096-52-5
MW: 216.3 D
From 280.00€ *
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5-methoxy DPT
5-methoxy DPT

Item number: Cay17297-5

5-methoxy DPT is a substituted form of DPT that is also an analog of 5-methoxy DiPT (Cay-11865), a psychoactive monoamine re-uptake inhibitor. The physiological and toxicological properties of this compound are not known. 5-methoxy DPT is regulated as a Schedule I compound in the United States. This product is...
Keywords: 5-methoxy-N,N-Dipropyltryptamine, 5-MeO DPT, 5-methoxy-N,N-dipropyl-1H-indole-3-ethanamine
Application: Analytical reference standard, Substituted DPT, 5-methoxy DiPT analog
CAS 69496-75-9
MW: 274.4 D
From 280.00€ *
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5-methoxy EPT (hydrochloride)
5-methoxy EPT (hydrochloride)

Item number: Cay17298-5

5-methoxy EPT (hydrochloride) (Cay-17298) is an analytical reference material that is classified as a tryptamine. It was detected in designer drugs purchased in an illegal market in Japan. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and...
Keywords: 5-methoxy-N-ethyl-N-Propyltryptamine, N-ethyl-5-methoxy-N-propyl-1H-indole-3-ethanamine, monohydrochloride
Application: Analytical reference material, Tryptamine, Physiological/toxicological properties unknown
CAS 2749303-04-4
MW: 296.8 D
From 280.00€ *
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TMA-DPH
TMA-DPH

Item number: Cay17294-5

TMA-DPH is a fluorescent probe used for measuring membrane fluidity in artificial and living membrane systems. The cylindrical shape of TMA-DPH confers high sensitivity to reorientation resulting from changes in surrounding lipids. TMA-DPH has excitation and emission maxima at 355 and 430 nm, respectively.Formal...
Keywords: N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl)phenylammonium (p-toluenesulfonate),...
Application: Fluorescent membrane fluidity probe
CAS 115534-33-3
MW: 461.6 D
From 60.00€ *
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IMD 0354
IMD 0354

Item number: Cay17290-5

IMD 0354 is an IKKbeta (IKK2) inhibitor that blocks NF-kappaB phosphorylation (IC50 = ~250 nM) and subsequent NF-kappaB p65 nuclear translocation. It exhibits cardioprotective properties by decreasing expression of P-selectin and ICAM-1 in the vasculature and blocking cardiomyocyte IL-1beta and MCP-1 production,...
Keywords: IKK2 Inhibitor V, N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxy-benzamide
Application: IKK2 inhibitor
CAS 978-62-1
MW: 383.7 D
From 50.00€ *
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NPPB
NPPB

Item number: Cay17292-25

NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Galphai/o and GPR35-Galpha16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial...
Keywords: HOE 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid
Application: GPR35 agonist, chloride channel blocker
CAS 107254-86-4
MW: 300.3 D
From 76.00€ *
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