- Search results for Cay10504-100
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16 products were found matching "Cay10504-100"!
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Item number: Cay10500-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
Keywords: | PAD4, PADI4, HL-60 PAD, HL-60 PAD, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine... |
Application: | Enzyme activity |
MW: | 78.8 kD |
From 570.00€
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Item number: Cay10009594-100
Pseudomonas aeruginosa (P. aeruginosa) is a common pathogen affecting immunocompromised patients with acute diseases such as pneumonia and vasculitis or chronic diseases such as cystic fibrosis. It produces several phenazine toxic metabolites, the most predominant of which is a blue pigment, pyocyanin. Pyocyanin,...
Keywords: | Pyocyanine, Sanasin, Sanazin, 5-methyl-1(5H)-phenazinone |
Application: | Apoptosis inducer |
CAS | 85-66-5 |
MW: | 210.2 D |
From 78.00€
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Item number: Cay10006594-100
Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor). It reduces U-46619-induced aggregation of platelets in isolated human platelet-rich plasma when used at a concentration of 5 µM. It decreases 1-lipoxygenase (1-LO) levels in the endothelial...
Keywords: | DuP-753, MK 954, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol,... |
Application: | AT1 receptor antagonist |
CAS | 124750-99-8 |
MW: | 461 D |
From 23.00€
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Item number: Cay10009584-100
2,3-dinor Thromboxane B2-d9 (2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 2,3-dinor TXB2 (Cay-19050) by GC- or LC-MS. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 2,3-dinor...
Keywords: | 2,3-dinor TXB2-d9,... |
Application: | Internal standard, 2,3-dinor TXB2 quantification |
MW: | 351.5 D |
From 244.00€
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Item number: Cay10574-100
Suberohydroxamic acid (SBHA) is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 µM) and HDAC3 (IC50 = 0.30 µM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. HDAC inhibitors, including SBHA, act synergistically to kill cancer cells when used...
Keywords: | SBHA, Suberic bis-Hydroxamic Acid, N1,N8-dihydroxy-octanediamide |
Application: | Histone deacetylase inhibitor |
CAS | 38937-66-5 |
MW: | 204.2 D |
From 38.00€
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Item number: Cay10534-100
(R)-Bromoenol lactone-d7 ((R)-BEL-d7) is intended for use as an internal standard for the quantification of (R)-BEL by GC- or LC-MS. The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent...
Keywords: | (R)-BEL-d7, 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl-2,3,4,5,6,7,8-d7)-2H-pyran-2-one |
Application: | GC/LC standard |
MW: | 324.2 D |
From 50.00€
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Item number: Cay14500-100
Coomassie blue R-250 is a dye that is commonly used in laboratories to stain or quantify proteins. It is a sensitive stain for protein detection in polyacrylamide gels, typically giving blue bands on a clear background with a sensitivity of 50-100 ng/band. It may be combined with other stains, such as silver stain,...
Keywords: | C.I. 42660,... |
Application: | Protein staining |
CAS | 6104-59-2 |
MW: | 826 D |
From 43.00€
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Item number: Cay15040-100
SKF 525A is a widely used, nonspecific cytochrome P (CYP)450 inhibitor that demonstrates 100% inhibition of the various CYP450 isoforms at 1-100 µM. It therefore potentiates the effects of many different drugs by inhibiting their metabolism (IC50 values in the µM range when tested using human liver microsomes). SKF...
Keywords: | RP 5171, U 5446, alpha-phenyl-alpha-propyl-benzeneacetic acid, 2-(diethylamino)ethyl ester, monohydrochloride |
Application: | CYP450 inhibitor |
CAS | 62-68-0 |
MW: | 390 D |
From 77.00€
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Item number: Cay15004-100
Azithromycin is a macrolide antibiotic. It is active against S. pneumoniae, S. aureus, N. gonorrhoeae, M. pneumoniae, H. pylori, C. trachomatis, and H. influenzae in vitro (MIC90s = S. pyogenes, S. pneumoniae, E. faecalis, or H. influenzae infection (ED50s = 0.78, 8.7, 12.7, and 30.3 mg/kg, respectively). It...
Keywords: | CP 62,993,... |
Application: | Antibiotic |
CAS | 83905-01-5 |
MW: | 749 D |
From 77.00€
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Item number: Cay10504-50
The Fatty Acid Screening Library contains more than 75 compounds of fatty acids with diverse biological activities in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. The library may also include some of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic,...
Application: | Screening |
1,978.00€
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Item number: Cay10054-10
The liver X receptors, LXRalpha and LXRbeta, are nuclear receptors that act as ligand-dependent transcription factors. They modulate cholesterol, fatty acids, and glucose homeostasis. GW 3965 is an orally-active agonist of LXRalpha and LXRbeta, activating the human isoforms with EC50 values of 190 and 30 nM,...
Keywords: | 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic acid, monohydrochloride |
Application: | LXR alpha / beta agonist |
CAS | 405911-17-3 |
MW: | 618.5 D |
From 53.00€
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Item number: Cay10004675-100
NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate (NADPH, Cay-9000743). It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the...
Keywords: | Coenzyme II, Nicotinamide adenine dinucleotide phosphate, TPN, beta-NADP, adenosine 5'-(trihydrogen diphosphate),... |
Application: | Cofactor |
CAS | 698999-85-8 |
MW: | 765.4 D |
From 46.00€
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