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Anti-FTO, NT (Alpha-ketoglutarate-dependent Dioxygenase FTO, Fat Mass And Obesity-associated Protein, KIAA1752)

ART NR.: F9103-50A.200 (200 µl)

Hersteller: USBio

Datenblatt

Anwendungen: ELISA, IHC, WB

Format: affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: Synthetic peptide selected from the N-terminal region of human FTO (KLH).

Lagerung: -20°C

Versand: +4°C

UniProt ID: Q9C0B1 | Suche mit UniProt ID

Gene ID: Gene ID 79068 | Suche mit Gene ID

Schlagworte: EC=1.14.11.-, Anti-Fat mass and obesity-associated protein, Anti-Alpha-ketoglutarate-dependent dioxygenase FTO

F9103-50A.200

200 µl

572 €

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Bemerkungen: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation. [The UniProt Consortium]
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