FLT3 Ligand (human):Fc (human) (rec.)

FLT3 Ligand (human):Fc (human) (rec.)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40B-0119-C010 10 µg -

3 - 9 business days*

10 %
248.00€
223.20€
AG-40B-0119-3010 30 µg (3 x 10 µg) -

3 - 9 business days*

10 %
495.00€
445.50€
AG-40B-0119-C100 100 µg -

3 - 9 business days*

10 %
963.00€
866.70€
 
The receptor-binding domain of human FLT3L is fused at the N-terminus to the Fc portion of human... more
Product information "FLT3 Ligand (human):Fc (human) (rec.)"
The receptor-binding domain of human FLT3L is fused at the N-terminus to the Fc portion of human IgG1. Liquid. In PBS (sterile). FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
Keywords: Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0119

Properties

Application: Bioassay
Conjugate: No
Host: Hamster cells
Species reactivity: human, mouse
Format: Liquid

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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