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(S)-H-1152 (hydrochloride)
(S)-H-1152 (hydrochloride)

Item number: Cay10007653-1

Rho-associated kinase (ROCK), activated by GTP-linked Rho, phosphorylates targets that are involved in cytoskeletal remodeling, smooth muscle contraction, and neuronal development. H-1152 is a potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM). It is a more potent inhibitor of ROCK...
Keywords: 5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methyl-isoquinoline, dihydrochloride
Application: ROCK inhibition
CAS 451462-58-1
MW: 392.3 D
From 48.00€ *
Review
Human HSP-60/HSPD1 (Heat Shock Protein 60) CLIA Kit
Human HSP-60/HSPD1 (Heat Shock Protein 60) CLIA Kit

Item number: E-CL-H1152.24

Type: Sandwich. Detection Range: 0.31~20ng/mL. Sensitivity: 0.19ng/mL. Tested Sample Types: Serum, Plasma, Cell supernatant. Test principle: This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human HSP-60/HSPD1 . Standards or...
Keywords: CPN60, Hsp60, HSP60, HSPD1, HSP-60, HuCHA60, EC=3.6.4.9, Chaperonin 60, 60 kDa chaperonin, Heat shock protein 60, P60...
Application: CLIA
Species reactivity: human
From 142.00€ *
Review
Human HSP-60/HSPD1 (Heat Shock Protein 60) CLIA Kit
Human HSP-60/HSPD1 (Heat Shock Protein 60) CLIA Kit

Item number: E-CL-H1152.96

Type: Sandwich. Detection Range: 0.31~20ng/mL. Sensitivity: 0.19ng/mL. Tested Sample Types: Serum, Plasma, Cell supernatant. Test principle: This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human HSP-60/HSPD1 . Standards or...
Keywords: CPN60, Hsp60, HSP60, HSPD1, HSP-60, HuCHA60, EC=3.6.4.9, Chaperonin 60, 60 kDa chaperonin, Heat shock protein 60, P60...
Application: CLIA
Species reactivity: human
541.00€ *
Review
H1152
H1152

Item number: SYN-1221-M001

Solid. Soluble in DMSO. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling,...
Keywords: (S)-4-Methyl-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride, H1152
Application: Cell-permeable ROCK inhibitor
CAS 871543-07-6
MW: 392,3 D
From 106.00€ *
Review