- Search results for Cay11871-50
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10 products were found matching "Cay11871-50"!
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Item number: Cay11851-10
Bacopaside X is a triterpenoid saponin that has been found in B. monniera and has antifungal and anticancer activities. It inhibits the growth of the fungi C. albicans, C. neoformans, and A. fumigatus (MIC = 50 µg/ml for all). Bacopaside X decreases the proliferation of MDA-MB-231, SHG44, HCT8, A549, and PC3M cancer...
Keywords: | Jujubogenin isomer of Bacopasaponin C, Bacopaside VII, (3beta,16beta,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl... |
Application: | Antifungal, Anticancer triterpenoid saponin |
CAS | 94443-88-6 |
MW: | 899.1 D |
From 125.00€
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Item number: Cay11817-500
Artesunate is a derivative of artemisinin (Cay-11816) that is active against P. falciparum in vitro (IC50 = 1.28 nM). It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. It inhibits the activity of the P. falciparum EXP1, a glutathione...
Keywords: | Artesunic Acid, NSC 712571, WR 256283, butanedioic acid,... |
Application: | Inflammation studies |
CAS | 88495-63-0 |
MW: | 384.4 D |
From 85.00€
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Item number: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Keywords: | 5-L-isoleucine-angiotensin II, acetate |
Application: | Peptide hormone |
CAS | 68521-88-0 |
MW: | 1046.2 D |
From 34.00€
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Item number: Cay17118-50
Niclosamide is a molluscicide. It is toxic to H. trivolvis snail eggs, juveniles, and adults (LC50s = 0.035, 0.044, and 0.11 mg/kg, respectively), as well as rainbow trout, white sucker, and fathead minnow (LC50s = 0.03, 0.09, and 0.11 mg/L, respectively). Niclosamide induces cell cycle arrest at the G0/G1 phase and...
Keywords: | BAY-6076, BAY-73, Bayluscide, HL 2448, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-benzamide compd. with 2-aminoethanol |
Application: | Anthelmintic, molluscicide |
CAS | 1420-04-8 |
MW: | 388.2 D |
From 36.00€
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Item number: Cay11781-500
MAM2201 (Cay-9001219) is a synthetic cannabinoid (CB) that is closely related, structurally, to AM2201 (Cay-10707), a compound which displays high affinities for both CB receptors. MAM2201 N-(3-fluoropentyl) isomer differs from MAM2201 by having fluorine at the 3 position rather than the 5 position of the alkyl...
Keywords: | [1-(3-fluoropentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid analog |
CAS | 1797983-61-9 |
MW: | 373.5 D |
From 235.00€
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Item number: Cay11801-5
ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of MLCK than its parent compound ML-9 (Cay-10010236).Formal Name:...
Keywords: | hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine, monohydrochloride |
Application: | MLCK inhibitor |
CAS | 110448-33-4 |
MW: | 452.7 D |
From 82.00€
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Item number: Cay17851-500
Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes metabolism of ethylene glycol and methanol to toxic metabolites. At 10 µM in monkeys, it can prevent the formation of toxic alcohol metabolites that generate metabolic acidosis. This compound is typically used as an antidote...
Keywords: | 4-Methylpyrazole, 4-methyl-1H-pyrazole |
Application: | Alcohol dehydrogenase inhibitor |
CAS | 7554-65-6 |
MW: | 82.1 D |
From 60.00€
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Item number: Cay11879-50
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1. Because of its protective...
Keywords: | Bis(2-hydroxybenzylidene)acetone, (1E,4E)-1,5-bis(2-hydroxyphenyl)-1,4-pentadien-3-one |
Application: | Detoxification studies |
CAS | 131359-24-5 |
MW: | 266.3 D |
From 88.00€
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Item number: Cay11876-50
L-alpha-Hydroxyglutaric acid (L-2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate (alpha-ketoglutarate) by L-2-hydroxyglutarate dehydrogenase, and mutations in this enzyme lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased L-2-HG levels. L-2-HG is structurally...
Keywords: | (S)-2-Hydroxypentanedioic Acid, L-2-HG, L-2-Hydroxyglutarate, L-2-Hydroxyglutaric Acid, 2S-hydroxy-pentanedioic acid,... |
Application: | PSMA inhibitor |
CAS | 63512-50-5 |
MW: | 194.1 D |
From 43.00€
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Item number: Cay11170-5
Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester (Cay-13679) is an impurity generated in the production of fluprostenol isopropyl ester....
Keywords: | 13(S),14(S)-epoxy Travoprost, Epoxy Derivative 2, (Z)-isopropyl... |
Application: | FP receptor agonist |
MW: | 516.6 D |
From 152.00€
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