- Search results for Cay11871
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7 products were found matching "Cay11871"!
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Item number: Cay11187-1
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
Application: | BRD4 inhibitor |
CAS | 1268524-70-4 |
MW: | 457 D |
From 35.00€
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Item number: Cay11877-1
AB-005 (Cay-11766) is a synthetic cannabinoid (CB) built on a 1-[(1-methylpiperidin-2-yl)methyl]-indole base that is characteristic of a series of potent CBs, including AM1220 (Cay-9001055), AM1241 (Cay-10010118), and AM1248 (Cay-11282). AB-005 azepane isomer is a variant of AB-005 in which the methylpiperidine...
Keywords: | [1-(hexahydro-1-methyl-1H-azepin-3-yl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid variant |
CAS | 1445751-74-5 |
MW: | 352.5 D |
From 109.00€
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Item number: Cay11887-1
Protodioscin is a steroidal saponin first isolated from plants used in herbal remedies. It displays cytotoxicity against a range of cancer cells in vitro, including leukemia, colon cancer, and prostate cancer cells (GI50 = 2 µM). Protodioscin, as a part of an extract from the plant T. terrestris, also improves...
Keywords: | NSC 698796, (3beta,22alpha,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl... |
Application: | Steroidal saponin, Anticancer |
CAS | 55056-80-9 |
MW: | 1049.2 D |
From 50.00€
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Item number: Cay18777-1
Altiratinib is a multiple kinase inhibitor, blocking Met, Tie2, VEGF2, TrkA, TrkB, and TrkC with IC50 values of 2.7, 8.0, 9.2, 0.85, 4.6, and 0.83 nM, respectively. It also inhibits several mutant Met isoforms at nanomolar concentrations. Altiratinib inhibits the proliferation of several cancer cell lines in vitro...
Keywords: | N-[4-[[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
Application: | MET / TIE2 / VEGFR2 inhibitor |
CAS | 1345847-93-9 |
MW: | 510.5 D |
From 43.00€
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Item number: Cay18771-1
The liver X receptors (LXRs) are nuclear receptors that act as ligand-dependent transcription factors. They modulate lipid, cholesterol, and carbohydrate metabolism and homeostasis. SR9238 is an inverse agonist of the two LXR isoforms, LXRalpha and LXRbeta (IC50s = 214 and 43 nM, respectively). It displays liver...
Keywords: | 5-[[[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylic... |
Application: | LXRA / LXRB inverse agonist |
CAS | 1416153-62-2 |
MW: | 595.7 D |
From 44.00€
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Item number: Cay18871-200
C-6 NBD is a derivative of the environmentally sensitive fluorophore nitrobenzoxadiazole (NBD, absorbance 465 nm, emission 535 nm). It is modified with a hexanoic acid tail, which provides a reactive carboxylic acid site. C-6 NBD has been used to synthesize a variety of fluorescently tagged compounds for research...
Keywords: | 6-(7-Nitrobenzofurazan-4-ylamino)hexanoic Acid, C6-NBD, NBD Hexanoic Acid, NBD-X,... |
Application: | Fluorophore, Compound tagging |
CAS | 88235-25-0 |
MW: | 294.3 D |
From 254.00€
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Item number: Cay11878-1
Curcuminoids are natural and synthetic analogs of curcumin (Cay-81025), a natural polyphenol with modulating effects in inflammation, cancer, and immunity. Salicylcurcumin is a synthetic curcuminoid which, like bisdemethoxycurcumin (Cay-10960), lacks methoxy groups on both phenols. Furthermore, the hydroxyl groups...
Keywords: | Salicylcurcuminoid, (1E,4Z,6E)-5-hydroxy-1,7-bis(2-hydroxyphenyl)-1,4,6-heptatrien-3-one |
Application: | Curcumin analog, Antioxidant |
CAS | 1236545-54-2 |
MW: | 308.3 D |
From 109.00€
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