- Search results for Cay10007965
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7 products were found matching "Cay10007965"!
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Item number: Cay10007965-5
FK-506 is a potent immunosuppressant in the same molecular class as cyclosporin A (Cay-12088) and rapamycin (Cay-13346). Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex then inhibits the activity of the...
Keywords: | Tacrolimus,... |
Application: | Immunosuppressant |
CAS | 104987-11-3 |
MW: | 804 D |
From 48.00€
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Item number: Cay10796-5
(±)-JWH 018 N-(4-hydroxypentyl) metabolite (Cay-10796) is an analytical reference standard categorized as a synthetic cannabinoid metabolite. (±)-JWH 018 N-(4-hydroxypentyl) metabolite is a metabolite of JWH 018 (Cay-27973, Cay-10900, Cay-13169). This product is intended for research and forensic applications.Formal...
Keywords: | 4-OH-JWH 018, (1-(4-hydroxypentyl)-1H-indol-3-yl)(naphthalen-1-yl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid metabolite |
CAS | 1320363-47-0 |
MW: | 357.5 D |
From 158.00€
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COVID-19 Research
Item number: Cay10007963-5
E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...
Keywords: | (2S,3S)-3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic... |
Application: | Cysteine protease inhibitor |
CAS | 66701-25-5 |
MW: | 357.4 D |
From 73.00€
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COVID-19 Research
Item number: Cay10007964-5
E-64c is an active metabolite of the protease inhibitor E-64d (Cay-13533). E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when...
Keywords: | Loxistatin Acid, NSC 694279,... |
Application: | Cysteine protease inhibitor |
CAS | 76684-89-4 |
MW: | 314.4 D |
From 84.00€
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Item number: Cay10007896-5
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators...
Keywords: | C6-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-hexanamide |
Application: | Bioactive lipid assays |
CAS | 147852-83-3 |
MW: | 199.2 D |
From 43.00€
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Item number: Cay10009796-5
CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...
Keywords: | 1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine |
Application: | SIRT1 activator |
CAS | 374922-43-7 |
MW: | 418.4 D |
From 40.00€
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Lipid-based Drug Delivery Tools
Item number: Cay10007946-5
C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin...
Keywords: | N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine, Palmitoyl Sphingomyelin, SM(d18:1/16:0), Sphingomyelin (d18:1/16:0),... |
Application: | Bioactive Lipid Assays |
CAS | 6254-89-3 |
MW: | 703 D |
From 94.00€
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