8 products were found matching "AG-40A-0099-C010"!

Human FGF-21 (amino acids 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction...

GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis). GITRL is constitutively expressed and released as soluble form by solid tumors and...

IL-36beta(mouse) (aa 31-183) is untagged. Induces secretion of IL-6 in BMDCs at a concentration of 10 ng - 100 ng/ml. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of...

Mouse FGF-21 (amino acids 1-210) is fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4...

Rat RBP4 (amino acids 19-201) is fused at the N-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Retinol binding protein 4 (RBP4, RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...

Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The UniProt Consortium] The fibroblast growth factor (FGF) family is a group of multifunctional...

Recombinant protein. Mouse vaspin (aa 21-413) is fused at the N-terminus to a FLAG(R)-tag. Produced in HEK 293 cells. Endotoxin: 95% (SDS-PAGE). Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both...