10 products were found matching "AG-40A-0098-C050"!

The extracellular domain of mouse GITRL (amino acids 45-173) is fused at the N-terminus to a FLAG(R)-tag. Induces GITR-mediated NF-kappaB activation in HEK 293 cells. Liquid. 0.2µm-filtered solution in 10mM glycine, pH 10.0. GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC),...

Human FGF-21 (amino acids 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction...

Rat Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the N-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the...

Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a His-tag. Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Lyophilized. Salt-free. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine...

Mouse FGF-21 (amino acids 1-210) is fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...

The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...

Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The UniProt Consortium] The fibroblast growth factor (FGF) family is a group of multifunctional...

FABP1 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. FABP1 is required for cholesterol synthesis...