9 products were found matching "AG-40A-0098-C010"!

Human FGF-21 (amino acids 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction...

Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a His-tag. Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Lyophilized. Salt-free. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine...

IL-36alpha (mouse) (aa 8-160) is untagged. Induces secretion of IL-6 in BMDCs at a concentration of 100 ng - 1 µg/ml. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of...

Mouse FGF-21 (amino acids 1-210) is fused at the C-terminus to the Fc portion of human IgG. Liquid. 0.2µm-filtered solution in PBS. FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4...

Rat Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the N-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the...

Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R...

Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The UniProt Consortium] The fibroblast growth factor (FGF) family is a group of multifunctional...

Recombinant protein. Mouse vaspin (aa 21-413) is fused at the N-terminus to a FLAG(R)-tag. Produced in HEK 293 cells. Endotoxin: 95% (SDS-PAGE). Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both...