Signal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS, pH 7.2. FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Cat-Nr: AG-40A-0187-C050
Menge: 50 µg
Preis: 429 €
UniProt ID: O95750 (Protein knowledgebase)
Schlagworte:
Fibroblast Growth Factor 19
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- FGF-19 (human) (rec.), Kat #: AG-40A-0186-C050
- FGF-19 (human) (rec.), Kat #: AG-40A-0186-C010
- FGF-19 (human):Fc (human) (rec.), Kat #: AG-40A-0187-C010
- FGF-19 (human, rec.) (His), Kat #: AG-40A-0111-C050
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- Fibroblast Growth Factor 19 (FGF19), human recombinant (rHuFGF19), Kat #: F4212-91B.25
- Fibroblast Growth Factor-19 (FGF19), human recombinant (rHuFGF19), Kat #: 97315.5
- Fibroblast Growth Factor-19 (FGF19), human recombinant (rHuFGF19), Kat #: 97315.1
- Fibroblast Growth Factor-19 (FGF19), human recombinant (rHuFGF19), Kat #: 97315.25
- Fibroblast Growth Factor-19, His Tag, human recombinant (rHuFGF-19-His), Kat #: 94912.1
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Products for: FGF - fibroblast growth factor
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