Detection Type: Colorimetric. Assay Type: Sandwich 96 well assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Caspase-1 is the best-described inflammatory caspase. It...

B7 family of immunoregulatory proteins is composed of ten members: B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1), B7-DC (PD-L2), B7-H2, B7-H3, B7-H4, B7-H5 (VISTA), B7-H6 and B7-H7. B7-H3 (or CD276) is a 316aa long type I transmembrane protein. B7-H3 shares 20-27% amino acid identity with other B7 family ligands....

Programmed cell death is a key mechanism involved in several biological processes ranging from development and homeostasis to immunity. Apoptosis, pyroptosis and NETosis are three well-studied modes of cell death. Pyroptosis is a form of necrotic cell death that has emerged as an important innate immune mechanism...