11 products were found matching "Cay9001958-5"!

2C-T-7 (Cay-11200) is a psychoactive 2,5-dimethoxy phenethylamine with a propylthio group in the 4 position. 25T7-NBOMe is a derivative of 2C-T-7, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition...

APY0201 is an inhibitor of FYVE finger-containing phosphoinositide kinase (PIKFYVE, IC50 = 5.2 nM) that selectively inhibits interleukin-12 (IL-12) family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-alpha in stimulated human peripheral blood mononuclear cells...

PTI-1 is a synthetic cannabinoid (CB) that contains the 1-pentyl-indole structure found in potent agonists of the central cannabinoid (CB1) receptor, like JWH 018 (Cay-10900), linked to a thiazole-based side chain. The physiological and toxicological properties of this compound have not been tested. This product is...

PTI-2 is a synthetic cannabinoid (CB) that contains the 1-pentyl-indole structure found in potent agonists of the central cannabinoid (CB1) receptor, like JWH 018 (Cay-10900), linked to a thiazole-based side chain. The physiological and toxicological properties of this compound have not been tested. This product is...

JWH 200 (Cay-10902) is a synthetic cannabinoid (CB) receptor agonist that binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM). Structurally, JWH 200 features a (4-morpholinyl)ethyl group attached to the indole amide of a 1H-indol-3-yl-(1-naphthyl)-methanone scaffold. JWH 200 analog 1 differs from JWH 200...

2C-T-4 (Cay-11892) is described formally as 2,5-dimethoxy-4-(isopropylthio)phenethylamine. The physiological and toxicological effects of this designer drug have not been investigated, although there is a case report of 2C-T-4 causing acute psychosis. 25T4-NBOMe is a derivative of 2C-T-4, characterized by the...

Arachidonoyl m-Nitroaniline (AmNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate...

JWH 011 is a synthetic cannabinoid (CB). This N-(1-methylhexyl) compound is analogous to the N-hexyl JWH 004, also a 2-methyl indole, which has high affinities for both central CB1 and peripheral CB2 receptors (Ki = 48 and 4.02 nM, respectively). This product is intended for forensic and research applications.Formal...

Cholesterol-doxorubicin (Chol-DOX) is a prodrug form of the anticancer agent doxorubicin (DOX, Cay-15007). Chol-DOX, when combined with tocopherol polyethylene glycol succinate/tocofersolan (TPGS, Cay-34661) in nanoassemblies, reduces MCF-7 and MDA-MB-231 breast cancer cell viability.Formal Name:...

EIDD-1931 is a ribonucleoside analog with antiviral activity. It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 µM, respectively). It...

1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm). It detects the ion via diffusion-limited collisional quenching.Formal Name:...