- Search results for Cay10004111
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5 products were found matching "Cay10004111"!
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Item number: Cay10005186-5
CAY10441 is an antagonist of the IP receptor. It is selective for the IP receptor over the prostaglandin E2 (PGE2) receptor subtypes EP1, EP2, EP3, and EP4, the FP and TP receptors, and a panel of 30 other receptors and ion channels but does bind to the alpha2A-adrenergic and imidazoline I2 receptors. CAY10441...
Keywords: | RO1138452, 4,5-dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imadazol-2-amine |
Application: | cAMP blocker |
CAS | 221529-58-4 |
MW: | 309.4 D |
From 201.00€
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Item number: Cay10044-1
PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress. It is found as a component in mildly oxidized LDL (MM-LDL) and in products formed from the oxidation of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (Ox-PAPC). PGPC activates peroxisome proliferator-activated receptor...
Keywords: | 1-Hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine, 1-Palmitoyl-2-glutaryl phosphatidylcholine,... |
Application: | Oxidized phospholipid |
CAS | 89947-79-5 |
MW: | 609.7 D |
From 35.00€
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Item number: Cay11004-1
Podoplanin is a transmembrane glycoprotein that has roles in development, immunology, and cancer. It is composed of a glycosylated extracellular domain, which is critical for podoplanin-induced platelet activation, a single transmembrane region that associates with CD9 and CD44, and a short cytoplasmic tail that...
Keywords: | Aggrus, gp38, T1A |
Application: | FC, WB |
Host: | Rat |
Species reactivity: | human |
287.00€
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Item number: Cay11041-250
Sterol regulatory element binding protein 2 (SREBP-2) regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. When cellular sterol levels are high, SREBP is bound by SCAP and Insig to ER membranes as a glycosylated...
Keywords: | NSC 4644, Trochol, lup-20(29)-ene-3beta,28-diol |
Application: | Cholesterol control |
CAS | 473-98-3 |
MW: | 442.7 D |
From 43.00€
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Item number: Cay10009411-1
The p90 ribosomal S6 kinases (RSKs) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic...
Keywords: | RSK2 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | rat |
564.00€
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