Eicosapentaenoic Acid ethyl ester-d5

Eicosapentaenoic acid ethyl ester-d5 is intended for use as an internal standard for the quantification of eicosapentaenoic acid ethyl ester (Cay-10008884) by GC- or LC-MS. Eicosapentaenoic acid (EPA) ethyl ester is an esterified form of the omega-3 fatty acid EPA (Cay-90110, Cay-90110.1, Cay-21908). Dietary administration of EPA ethyl ester (41.4 g/100 g of total dietary fatty acids) increases the ex vivo activity of hepatic beta-oxidation enzymes. It also reduces total hepatic triglyceride levels and increases the omega-3 fatty acid content of hepatic triglycerides and phospholipids, as well as increases the total levels of omega-3 fatty acids in rats. EPA ethyl ester (1 g/kg) reverses increases in plasma cholesterol levels and reduces circulating triglyceride levels in rats fed a high-fat diet. Formulations containing eicosapentaenoic acid ethyl ester have been used as adjuncts in the treatment of hypertriglyceridemia.Formal Name: 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid, ethyl ester-d5. Synonyms: C20:5(5Z,8Z,11Z,14Z,17Z) ethyl ester-d5, EPA ethyl ester-d5, Icosapent ethyl-d5, SFE 22:5-d5. Molecular Formula: C22H29D5O2. Formula Weight: 335.5. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC([2H])([2H])C([2H])([2H])[2H])=O. InChi Code: InChI=1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17-/i2D3,4D2. InChi Key: SSQPWTVBQMWLSZ-GBJCQEPPSA-N.