- Search results for Cay15738
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5 products were found matching "Cay15738"!
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Item number: Cay15783-5
The anaphylatoxin C3a induces a range of responses by activating its G protein-coupled receptor, C3aR, resulting in calcium mobilization. SB 290157 is a non-peptide antagonist of C3aR, competitively blocking C3a binding with an IC50 value of 200 nM. It potently inhibits a wide variety of C3a-induced responses in...
Keywords: | N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-trifluoroacetate |
Application: | C3aR antagonist |
CAS | 1140525-25-2 |
MW: | 526.5 D |
From 60.00€
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Item number: Cay15873-1
Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental...
Keywords: | DHA-S, DHEAS, NSC 72822, 3beta-(sulfooxy)-androst-5-en-17-one, monosodium salt |
Application: | Dehydroepiandrosterone metabolite |
CAS | 1099-87-2 |
MW: | 390.5 D |
From 50.00€
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Item number: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
Keywords: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
Application: | Microtubule function studies, cell cycle arrest |
CAS | 31430-18-9 |
MW: | 301.3 D |
From 48.00€
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Item number: Cay13578-5
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2...
Keywords: | SU 5408, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester |
Application: | Mouse VEGFR2 inhibitor |
CAS | 15966-93-5 |
MW: | 310.4 D |
From 92.00€
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Item number: Cay15387-1
Galiellalactone is a fungal metabolite isolated from the ascomycetes G. rufa strain A75-86 and A111-95 that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells with an IC50 value of 0.25-0.5 µM. The selectivity of this compound is achieved by its ability to block the binding of activated STAT3 dimers...
Keywords: | (7bS)-5,5aR,6,7,7aR,7b-hexahydro-7b-hydroxy-4S-methyl-indeno[1,7-bc]furan-2(4H)-one |
Application: | JAK/STAT signal transduction inhibitor |
CAS | 133613-71-5 |
MW: | 194.2 D |
From 294.00€
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