5 products were found matching "Cay15738"!

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SB 290157 (trifluoroacetate salt)
SB 290157 (trifluoroacetate salt)

Item number: Cay15783-5

The anaphylatoxin C3a induces a range of responses by activating its G protein-coupled receptor, C3aR, resulting in calcium mobilization. SB 290157 is a non-peptide antagonist of C3aR, competitively blocking C3a binding with an IC50 value of 200 nM. It potently inhibits a wide variety of C3a-induced responses in...
Keywords: N2-[2-(2,2-diphenylethoxy)acetyl]-L-arginine, 2,2,2-trifluoroacetate
Application: C3aR antagonist
CAS 1140525-25-2
MW: 526.5 D
From 60.00€ *
Review
Dehydroepiandrosterone Sulfate (sodium salt)
Dehydroepiandrosterone Sulfate (sodium salt)

Item number: Cay15873-1

Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental...
Keywords: DHA-S, DHEAS, NSC 72822, 3beta-(sulfooxy)-androst-5-en-17-one, monosodium salt
Application: Dehydroepiandrosterone metabolite
CAS 1099-87-2
MW: 390.5 D
From 50.00€ *
Review
Nocodazole
Nocodazole

Item number: Cay13857-5

Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
Keywords: NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester
Application: Microtubule function studies, cell cycle arrest
CAS 31430-18-9
MW: 301.3 D
From 48.00€ *
Review
VEGFR2 Kinase Inhibitor I
VEGFR2 Kinase Inhibitor I

Item number: Cay13578-5

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2...
Keywords: SU 5408, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester
Application: Mouse VEGFR2 inhibitor
CAS 15966-93-5
MW: 310.4 D
From 92.00€ *
Review
Galiellalactone
Galiellalactone

Item number: Cay15387-1

Galiellalactone is a fungal metabolite isolated from the ascomycetes G. rufa strain A75-86 and A111-95 that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells with an IC50 value of 0.25-0.5 µM. The selectivity of this compound is achieved by its ability to block the binding of activated STAT3 dimers...
Keywords: (7bS)-5,5aR,6,7,7aR,7b-hexahydro-7b-hydroxy-4S-methyl-indeno[1,7-bc]furan-2(4H)-one
Application: JAK/STAT signal transduction inhibitor
CAS 133613-71-5
MW: 194.2 D
From 294.00€ *
Review