7 products were found matching "Cay15737-384"!
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CRT0066101 (hydrochloride)
Item number: Cay15337-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
| Keywords: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
| Application: | PKD inhibitor |
| CAS | 1781742-22-0 |
| MW: | 447.8 D |
From 46.00€
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Norketamine (hydrochloride)
Item number: Cay15787-1
Norketamine (hydrochloride) (Cay-15787) is an analytical reference material categorized as an arylcyclohexylamine metabolite. Norketamine is a metabolite of ketamine (Cay-19389, Cay-11630). This product is intended for research and forensic applications.Formal Name: 2-amino-2-(2-chlorophenyl)-cyclohexanone,...
| Keywords: | N-desmethyl Ketamine, 2-amino-2-(2-chlorophenyl)-cyclohexanone, monohydrochloride |
| Application: | Analytical reference material, Arylcyclohexylamine metabolite |
| CAS | 79499-59-5 |
| MW: | 260.2 D |
From 43.00€
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Galiellalactone
Item number: Cay15387-1
Galiellalactone is a fungal metabolite isolated from the ascomycetes G. rufa strain A75-86 and A111-95 that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells with an IC50 value of 0.25-0.5 µM. The selectivity of this compound is achieved by its ability to block the binding of activated STAT3 dimers...
| Keywords: | (7bS)-5,5aR,6,7,7aR,7b-hexahydro-7b-hydroxy-4S-methyl-indeno[1,7-bc]furan-2(4H)-one |
| Application: | JAK/STAT signal transduction inhibitor |
| CAS | 133613-71-5 |
| MW: | 194.2 D |
From 294.00€
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STAT5 Inhibitor
Item number: Cay15784-5
Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two...
| Keywords: | Signal Transducers and Activators of Transcription 5, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide... |
| Application: | Cell permeable STAT5 inhibitor |
| CAS | 285986-31-4 |
| MW: | 293.3 D |
From 92.00€
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Bicyclomycin Benzoate
Item number: Cay15384-5
Bicyclomycin benzoate is an antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria. It is inactive against Proteus, P. aeruginosa, and Gram-positive bacteria.Formal Name:...
| Keywords: | FR2054, 3'-benzoate bicyclomycin |
| Application: | Antibiotic |
| CAS | 37134-40-0 |
| MW: | 406.4 D |
From 189.00€
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SI-113
Item number: Cay37384-10
SI-113 is a serum/glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 = 600 nM). It is selective for SGK1 over c-Src and Abl kinases at 12.5 µM. SI-113 (12.5 µM) is cytotoxic to MCF-7 breast cancer, A172 glioblastoma multiforme, and RKO colorectal adenocarcinoma cell lines. In vivo, SI-113, in combination with...
| Keywords: | 2-[[1-(2-phenylethenyl)-4-[(2-phenylethyl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]-ethanol |
| Application: | SGK1 inhibitor |
| CAS | 1392816-46-4 |
| MW: | 400.5 D |
From 40.00€
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AZD 8186
Item number: Cay17384-1
AZD 8186 is a selective PI3Kbeta/delta inhibitor that exhibits IC50 values of 3, 17, and 752 nM for PI3Kbeta, delta, and alpha, respectively, in cells sensitive to isoform-specific PI3K inhibition. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 µM and...
| Keywords: | 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide |
| Application: | PI3Kbeta/delta inhibitor |
| CAS | 1627494-13-6 |
| MW: | 457.5 D |
From 43.00€
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