6 products were found matching "Cay15739"!

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MF498
MF498

Item number: Cay15973-1

Prostaglandin E2 (PGE2, Cay-14010) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. MF498 is a selective EP4 receptor antagonist (Ki...
Keywords: N-[[[4-(5,9-diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-benzeneac...
Application: EP4 receptor antagonist
CAS 915191-42-3
MW: 603.7 D
From 92.00€ *
Review
Piericidin A
Piericidin A

Item number: Cay15379-5

Complex I, also known as NADH:ubiquinone oxidoreductase or NADH dehydrogenase (ubiquinone), catalyzes the transfer of electrons from NADH to ubiquinone (also known as coenzyme Q10) as part of the respiratory chain leading to ATP generation. Piericidin A is an irreversible inhibitor of mitochondrial complex I that...
Keywords: AR 054, Shaoguanmycin B, SN 198E,...
Application: Mitochondrial Complex I inhibitor
CAS 2738-64-9
MW: 415.6 D
From 171.00€ *
Review
Salinomycin
Salinomycin

Item number: Cay13579-5

Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within...
Keywords: alpha-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[...
Application: Tumor growth inhibitor, Antiprotozoal, Coccidiostat
CAS 53003-10-4
MW: 751 D
From 34.00€ *
Review
2C-T (hydrochloride)
2C-T (hydrochloride)

Item number: Cay13957-10

A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances. 2C-T (hydrochloride) is described formally as...
Keywords: 2,5-Dimethoxy-4-methylthiophenethylamine, 2,5-dimethoxy-4-(methylthio)-benzeneethanamine, monohydrochloride
Application: Analytical reference standard, 2,5-dimethoxy phenethylamine derivative
CAS 61638-10-6
MW: 263.8 D
From 258.00€ *
Review
Pyrrolidine Linoleamide
Pyrrolidine Linoleamide

Item number: Cay17539-5

Linoleic acid (Cay-90150) is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Pyrrolidine linoleamide is a derivative of the amide of linoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251...
Keywords: 1-(1-pyrrolidinyl)-9Z,12Z-octadecadien-1-one
Application: Linoleic acid amide, antiproliferative
CAS 3140-51-0
MW: 333.6 D
From 43.00€ *
Review
MeBIO
MeBIO

Item number: Cay19573-5

MeBIO is a control analog of the GSK3alpha/beta inhibitor, BIO (Cay-13123). It displays minimal activity against Cdk1/Cyclin B, GSK3alpha/beta, and Cdk5/p25 (IC50s = 92.0, 44-100, and >100 µM, respectively). MeBIO has been identified as an aryl hydrocarbon receptor (AhR) agonist (EC50s = 20 and 93 nM for yeast and a...
Keywords: 1-Methyl-6-bromo-indirubin-3'-oxime, Me6BIO,...
Application: BIO control analog, AhR agonist
CAS 667463-95-8
MW: 370.2 D
From 43.00€ *
Review