- Search results for Cay17285
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7 products were found matching "Cay17285"!
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Item number: Cay17285-1
Protein arginine methyltransferases (PRMTs) target nuclear and cytoplasmic substrates and can alter protein actions and gene expression. PRMT5, which can methylate histones H2A, H3, and H4, ribonucleoproteins, and other proteins, is upregulated in several human cancers, including lymphomas. Moreover, suppression of...
Keywords: | GSK3235025, N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide |
Application: | PRMT5 inhibitor |
CAS | 1616391-65-1 |
MW: | 383.4 D |
From 66.00€
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Item number: Cay17289-5
Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel thought to be involved in osmoregulation, hyperalgesia, and control of epithelial cell volume. GSK1016790A is a TRPV4 agonist that has been reported to elicit calcium influx in HEK cells expressing mouse or human TRPV4 (EC50s = 18 and...
Keywords: | N-[(1S)-1-[[4-[(2S)-2-[[(2,4-dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]-... |
Application: | TRPV4 agonist |
CAS | 942206-85-1 |
MW: | 655.6 D |
From 43.00€
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Item number: Cay17283-5
ALEPH-4 is a homolog of 2,5-dimethoxy-4-methylthioamphetamine (DOT), a substituted amphetamine of the phenethylamine class of abused compounds. It contains an isopropyl group in place of the methyl group extending from the thiol on the amphetamine base structure. This product is intended for forensic and research...
Keywords: | 2,5-Dimethoxy-4-iso-propylthioamphetamine, 2,5-dimethoxy-alpha-methyl-4-[(1-methylethyl)thio]-benzeneethanamine |
Application: | Analytical reference material, Phenethylamine, Substituted amphetamine, DOT homolog |
CAS | 123643-26-5 |
MW: | 269.4 D |
From 98.00€
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Item number: Cay17284-5
ALEPH-2 is a homolog of 2,5-dimethoxy-4-methylthioamphetamine (DOT), a substituted amphetamine of the phenethylamine class of abused compounds. It contains an ethyl group in place of the methyl group extending from the thiol on the amphetamine base structure. This product is intended for forensic and research...
Keywords: | 2,5-Dimethoxy-4-ethylthioamphetamine, 4-(ethylthio)-2,5-dimethoxy-alpha-methyl-benzeneethanamine |
Application: | Analytical reference material, Phenethylamine, Substituted amphetamine, DOT homolog |
CAS | 185562-00-9 |
MW: | 255.4 D |
From 98.00€
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Item number: Cay17287-5
LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A (Ki = 52.7 nM) and 5-HT2A (Ki = 326 nM) receptors, respectively. It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56...
Keywords: | 4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide, monohydrochloride |
Application: | Serotonin 5-HT7 receptor agonist |
CAS | 824958-12-5 |
MW: | 488.1 D |
From 60.00€
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Item number: Cay17282-5
Cdc25 dual-specific protein tyrosine phosphatases are important for cell cycle progression and often overexpressed in cancers. Through the removal of inhibitory phosphates, they function to catalyze the activation of cyclin-Cdk complexes. DA-3003-2 is a Cdc25 phosphatase inhibitor (IC50 = 0.82 µM for human...
Keywords: | NSC 663285, 7-chloro-6-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione |
Application: | Cdc25 phosphatase inhibitor |
CAS | 383907-47-9 |
MW: | 321.8 D |
From 84.00€
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Item number: Cay17288-25
Pantothenic acid (vitamin B5) is a precursor in the biosynthesis of coenzyme A (Cay-16147), which is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Two enantiomers of pantothenic acid exist, D- or L-form. D-Pantothenic...
Keywords: | N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-beta-alanine, monosodium salt |
Application: | Vitamin B6 |
CAS | 867-81-2 |
MW: | 241.2 D |
From 96.00€
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