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EPZ005687
EPZ005687

Item number: Cay13966-5

EPZ005687 is a potent, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 24 nM), the enzymatic subunit of polycomb repressive complex 2 (PRC2). It acts competitively with the EZH2 substrate S-adenosylmethionine. EPZ005687 has greater than 500-fold selectivity against 15 other protein methyltransferases...
Keywords: 1-cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carbo...
Application: Lysine methyltranferase EZH2 inhibitor
CAS 1396772-26-1
MW: 539.7 D
From 115.00€ *
Review
MDL 72527 (hydrochloride)
MDL 72527 (hydrochloride)

Item number: Cay13996-25

MDL 72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase (IC50s = 6.1 and 0.02 µM, respectively). It does not inhibit monoamine oxidase or D-amino acid oxidase. MDL 72527 inhibits PAO-dependent H2O2 production in vitro and in vivo and is used to study the role of...
Keywords: N1,N4-di-2,3-butadien-1-yl-1,4-butanediamine, dihydrochloride
Application: PAO inhibitor
CAS 93565-01-6
MW: 265.2 D
From 50.00€ *
Review
Goat anti-Mouse IgG2a:SureLight(R) APC
Goat anti-Mouse IgG2a:SureLight(R) APC

Item number: Cay13396-1

Goat anti-Mouse IgG2a> conjugated to SureLight(R) APC, 100µg Antibody: Goat polyclonal anti-Mouse IgG2a Excitation max. lambda: 650 nm Emission max. lambda: 660 nm Uses: Flow cytometry/Fluorescence-activated cell sortingEmission: 660 nm. Excitation: 650 nm. Formulation: (Request formulation change), A lyophilized...
Application: IF
Host: Goat
Species reactivity: mouse
293.00€ *
Review